LOCUS       XP_018650675             715 aa            linear   INV 19-OCT-2016
DEFINITION  putative cyclic-nucleotide-gated cation channel [Schistosoma
            mansoni].
ACCESSION   XP_018650675
VERSION     XP_018650675.1
DBLINK      BioProject: PRJNA39937
DBSOURCE    REFSEQ: accession XM_018798825.1
KEYWORDS    RefSeq.
SOURCE      Schistosoma mansoni
  ORGANISM  Schistosoma mansoni
            Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
            Trematoda; Digenea; Strigeidida; Schistosomatoidea;
            Schistosomatidae; Schistosoma.
REFERENCE   1
  AUTHORS   Protasio,A.V., Tsai,J.I., Babbage,A., Nichol,S., Hunt,M., de
            Silva,N., Anderson,T.J.C., Clark,R.C., Davidson,C., Dillon,G.P.,
            Holroyd,N., LoVerde,P.T., Lloyd,C., McQuillan,J., Oliveira,G.,
            Otto,T.D., Parker-Manuel,S.J., Quail,M.A., Wilson,A., Zerlotini,A.,
            Dunne,D.W. and Berriman,M.
  TITLE     A systematically improved high quality genome and transcriptome of
            the human blood fluke Schistosoma mansoni
  JOURNAL   Unpublished
REFERENCE   2  (residues 1 to 715)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2016) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3
  AUTHORS   Aslett,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2011) to the INSDC. Sanger Institute, Wellcome
            Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to CCD78058.
FEATURES             Location/Qualifiers
     source          1..715
                     /organism="Schistosoma mansoni"
                     /strain="Puerto Rico"
                     /db_xref="taxon:6183"
                     /chromosome="3"
     Protein         1..715
                     /product="putative cyclic-nucleotide-gated cation channel"
                     /calculated_mol_wt=82992
     Region          101..356
                     /region_name="Ion_trans"
                     /note="Ion transport protein; pfam00520"
                     /db_xref="CDD:425730"
     Region          427..544
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(493..494,509..511)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(531..533,537..539)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          543..613
                     /region_name="CLZ"
                     /note="C-terminal leucine zipper domain of cyclic
                     nucleotide-gated channels; pfam16526"
                     /db_xref="CDD:435399"
     CDS             1..715
                     /locus_tag="Smp_194700"
                     /coded_by="XM_018798825.1:1..2148"
                     /db_xref="GeneID:8352031"
                     /db_xref="UniProtKB/TrEMBL:G4VGD7"
ORIGIN      
        1 maeivetpdi afqnlesrsk ssimkrlifc fskkykrekq ndsavenlii nkdteagdkk
       61 ndtnkqeteg etkkkltirq riqnipsnlk dlvidssesg yyywigivti tvlynaivlp
      121 mrsaftqfhe lspitwmvld ycidcvyfmd ifvgfrtgyl eegllvrdke klkqaylkrr
      181 qfiidiitil ptdllylipi fnhyaswlrf nrlmkiyrsf efvdrtetrt nrpnlfrism
      241 lttyilvlih wnaciyfgfs rasglssdsf vypprssddt sdeyknyteq wdrlfsqyvy
      301 sfywstlilt tigetpkpvr naeyifitid flvgvlifat vvgnvgamit nmnaartefq
      361 nkmdgvkrym efrkvnkele lrvirwfdyl wtnkqsleed slnalpdklk aeiaihvhfd
      421 tlqrvsifkd cdpgllvelv lklqlqvfsp gdyicrkgdi gkemyivkrg klsvvsedgk
      481 tvfvtlgegs vfgeisilni agnktgnrrs anvrsvgysd lfclskddlw dalteypetk
      541 tilmqrgqdi lrkdnllded ilrkaqeqqe sieqcvqrid ntmnqlttrl arligefgas
      601 qaklkrrltr leqeydmnss clvqdnnndn hspryrkysd qltndsqlpm nteseynrks
      661 iqtirqkqgi qlkinhkqrn tsnssstsiy dkreslsslg snitndtlpf vqdde
//