KEGG   REACTION: R00111Help
Entry
R00111                      Reaction                               

Name
N-(omega)-Hydroxyarginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)
Definition
NADPH + 2 N(omega)-Hydroxyarginine + 2 Oxygen + H+ <=> NADP+ + 2 Nitric oxide + 2 L-Citrulline + 2 H2O
Equation
C00005 + 2 C05933 + 2 C00007 + C00080 <=> C00006 + 2 C00533 + 2 C00327 + 2 C00001
Comment
the latter part of multi-step reaction (see R00557, R00558+R00111)
following after R00558
NADH (see R10108)
RPair
C00005_C00006 cofac [RC:RC00001]
C00001_C00007 leave
C00327_C05933 main [RC:RC01044]
C00007_C00327 leave
C00533_C05933 main [RC:RC02757]
Enzyme
Pathway
Arginine and proline metabolism
Orthology
K00491  
nitric-oxide synthase, bacterial [EC:1.14.13.39]
K13240  
nitric-oxide synthase, brain [EC:1.14.13.39]
K13241  
nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242  
nitric-oxide synthase, endothelial [EC:1.14.13.39]
K13253  
nitric-oxide synthase, invertebrate [EC:1.14.13.39]
K13427  
nitric-oxide synthase, plant [EC:1.14.13.39]

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