KEGG   REACTION: R00226Help
Entry
R00226                      Reaction                               

Name
pyruvate:pyruvate acetaldehydetransferase (decarboxylating);
(S)-2-acetolactate pyruvate-lyase (carboxylating)
Definition
(S)-2-Acetolactate + CO2 <=> 2 Pyruvate
Equation
Comment
TPP-dependent enzymatic reaction (R00014+R04672)
Reactant pair
C00022_C06010 main [RC:RC00106]
Enzyme
Pathway
Valine, leucine and isoleucine biosynthesis
Butanoate metabolism
C5-Branched dibasic acid metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of antibiotics
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Module
M00019  
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Orthology
K01652  
acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653  
acetolactate synthase I/III small subunit [EC:2.2.1.6]
K11258  
acetolactate synthase II small subunit [EC:2.2.1.6]

DBGET integrated database retrieval system