KEGG   REACTION: R00311Help
Entry
R00311                      Reaction                               

Name
protoheme,NADPH---hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
Definition
Heme + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Biliverdin + CO + Fe2+ + 3 [Oxidized NADPH---hemoprotein reductase] + 3 H2O
Equation
C00032 + 3 C03024 + 3 C00007 <=> C00500 + C00237 + C14818 + 3 C03161 + 3 C00001
Comment
multi-step reaction
Reaction class
C00032_C00500
Enzyme
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K00510  
heme oxygenase 1 [EC:1.14.14.18]
K21418  
heme oxygenase 2 [EC:1.14.14.18]

DBGET integrated database retrieval system