KEGG   REACTION: R00351Help
Entry
R00351                      Reaction                               

Name
acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
Definition
Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate
Equation
Comment
(pro-S)-carboxymethyl-forming (ec 2.3.3.1)
(pro-R)-carboxymethyl-forming (ec 2.3.3.3)
RPair
C00010_C00024 main [RC:RC00004]
C00036_C00158 main [RC:RC00067]
C00024_C00158 trans
C00001_C00158 leave
Enzyme
2.3.3.1         2.3.3.3
Pathway
Citrate cycle (TCA cycle)
Glyoxylate and dicarboxylate metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Module
M00009  
Citrate cycle (TCA cycle, Krebs cycle)
M00010  
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00012  
Glyoxylate cycle
Orthology
K01647  
citrate synthase [EC:2.3.3.1]

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