KEGG   REACTION: R00351Help
Entry
R00351                      Reaction                               

Name
acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
Definition
Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate
Equation
Comment
(pro-S)-carboxymethyl-forming (ec 2.3.3.1)
(pro-R)-carboxymethyl-forming (ec 2.3.3.3)
unknown stereospecificity (ec 2.3.3.16)
RPair
C00010_C00024 main [RC:RC00004]
C00036_C00158 main [RC:RC00067]
C00024_C00158 trans
C00001_C00158 leave
Enzyme
2.3.3.1         2.3.3.3         2.3.3.16
Pathway
Citrate cycle (TCA cycle)
Glyoxylate and dicarboxylate metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of antibiotics
Carbon metabolism
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Module
M00009  
Citrate cycle (TCA cycle, Krebs cycle)
M00010  
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00012  
Glyoxylate cycle
M00740  
Methylaspartate cycle
Orthology
K01647  
citrate synthase [EC:2.3.3.1]

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