KEGG   REACTION: R00575Help
Entry
R00575                      Reaction                               

Name
hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
Definition
2 ATP + L-Glutamine + HCO3- + H2O <=> 2 ADP + Orthophosphate + L-Glutamate + Carbamoyl phosphate
Equation
Comment
two-step reaction (see R00575+R00256)
RPair
C00002_C00008 ligase [RC:RC00002]
C00002_C00009 ligase
C00025_C00064 main [RC:RC00010]
C00002_C00169 trans
C00001_C00025 leave
C00064_C00169 main [RC:RC02750]
C00169_C00288 leave
Enzyme
Pathway
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Metabolic pathways
Orthology
K01954  
carbamoyl-phosphate synthase [EC:6.3.5.5]
K01955  
carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
K01956  
carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
K11540  
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541  
carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]

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