KEGG   REACTION: R00742Help
Entry
R00742                      Reaction                               

Name
Acetyl-CoA:carbon-dioxide ligase (ADP-forming)
Definition
ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate + Malonyl-CoA
Equation
Comment
two-step reaction (see R04385 + R04386)
RPair
C00002_C00008 ligase [RC:RC00002]
C00002_C00009 ligase
C00024_C00083 main [RC:RC00040]
C00083_C00288 main [RC:RC00367]
Enzyme
Pathway
Fatty acid biosynthesis
Tetracycline biosynthesis
Aflatoxin biosynthesis
Pyruvate metabolism
Propanoate metabolism
Carbon fixation pathways in prokaryotes
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Carbon metabolism
Fatty acid metabolism
Module
M00082  
Fatty acid biosynthesis, initiation
M00375  
Hydroxypropionate-hydroxybutylate cycle
M00376  
3-Hydroxypropionate bi-cycle
Orthology
K01961  
acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
K01962  
acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2]
K01963  
acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2]
K01964  
acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K02160  
acetyl-CoA carboxylase biotin carboxyl carrier protein
K11262  
acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
K11263  
acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
K15036  
acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K15037  
biotin carboxyl carrier protein
K18472  
acetyl/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3]
K18603  
acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K18604  
acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K18605  
biotin carboxyl carrier protein

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