KEGG REACTION: R00742

REACTION: R00742

Entry

R00742 Reaction

Name

Acetyl-CoA:carbon-dioxide ligase (ADP-forming)

Definition

ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate + Malonyl-CoA

Equation

C00002 + C00024 + C00288 <=> C00008 + C00009 + C00083

Comment

two-step reaction (see R04385 + R04386)

RPair

RP00003	C00002_C00008 ligase
RP00010	C00002_C00009 ligase
RP00124	C00024_C00083 main
RP01077	C00083_C00288 main

Enzyme

6.4.1.2

Pathway

rn00253	Tetracycline biosynthesis
rn00620	Pyruvate metabolism
rn00640	Propanoate metabolism
rn00720	Carbon fixation pathways in prokaryotes
rn01100	Metabolic pathways
rn01110	Biosynthesis of secondary metabolites
rn01120	Microbial metabolism in diverse environments

Orthology

K01961	acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
K01962	acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2]
K01963	acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2]
K01964	acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K02160	acetyl-CoA carboxylase biotin carboxyl carrier protein
K11262	acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
K15036	acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K15037	biotin carboxyl carrier protein

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (28)   
   KEGG PATHWAY (14)   
   KEGG MODULE (14)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (14)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
   KEGG RPAIR (4)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (7707)   
   KEGG ORTHOLOGY (8)   
   KEGG GENES (7699)   
All databases (7756)   

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