KEGG   REACTION: R01074Help
Entry
R01074                      Reaction                               
Name
biotin:CoA ligase (AMP-forming);
biotin:apo-[carboxylase] ligase (AMP-forming);
ATP:biotin adenylyltransferase
Definition
ATP + Biotin <=> Diphosphate + Biotinyl-5'-AMP
Equation
Comment
first step of two-step reaction (R01075, R04562, R04563, R04582 or R04604)
subsequently R05145 or R03762
RPair
C00002_C00013 leave
C00002_C05921 trans
C00120_C05921 main
Enzyme
6.2.1.11        6.3.4.9         6.3.4.10        6.3.4.11        
6.3.4.15
Pathway
Biotin metabolism
Metabolic pathways
Orthology
K01942  
biotin--protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15]
K01947  
biotin-[acetyl-CoA-carboxylase] ligase / type III pantothenate kinase [EC:6.3.4.15 2.7.1.33]
K03524  
BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
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