KEGG   REACTION: R01699Help
Entry
R01699                      Reaction                               

Name
pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)
Definition
Pyruvate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2
Equation
Comment
pyruvate dehydrogenase complex: pyruvate dehydrogenase
a part of multi-step reaction (see R00209, R01699+R02569+R07618)
subsequently R02569
TPP-dependent enzyme (see R00014+R03270)
RPair
C00011_C00022 leave
C00022_C16255 trans
C15972_C16255 main [RC:RC00627]
Enzyme
Orthology
K00161  
pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00162  
pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]
K00163  
pyruvate dehydrogenase E1 component [EC:1.2.4.1]

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