KEGG   REACTION: R01795
Entry
R01795                      Reaction                               
Name
L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
Definition
Tetrahydrobiopterin + L-Phenylalanine + Oxygen <=> Dihydrobiopterin + L-Tyrosine + H2O
Equation
C00272 + C00079 + C00007 <=> C00268 + C00082 + C00001
Comment
two-step reaction (see R07211+R04734)
Reaction class
RC00023  C00268_C00272
RC00490  C00079_C00082
Enzyme
1.14.16.1
Pathway
rn00360  Phenylalanine metabolism
rn00400  Phenylalanine, tyrosine and tryptophan biosynthesis
rn01100  Metabolic pathways
rn01230  Biosynthesis of amino acids
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.1
     R01795  Tetrahydrobiopterin + L-Phenylalanine + Oxygen <=> Dihydrobiopterin + L-Tyrosine + H2O
Orthology
K00500  phenylalanine-4-hydroxylase [EC:1.14.16.1]
Other DBs
RHEA: 30790

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (2609)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2608)   
All databases (2628)   

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