KEGG   REACTION: R01940
Entry
R01940                      Reaction                               
Name
2-oxoadipate:[dihydrolipoyllysine-residue succinyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating)
Definition
2-Oxoadipate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + CO2
Equation
C00322 + C15972 <=> C06157 + C00011
Comment
2-oxoadipate dehydrogenase complex: 2-oxoadipate dehydrogenase
a part of multi-step reaction (see R01933, R01940+R02571+R07618)
subsequently R02571
TPP-dependent enzyme (see R13166+R13167)
Reaction class
RC00627  C06157_C15972
RC02833  C00322_C06157
Enzyme
1.2.4.-
Module
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.-
     R01940  2-Oxoadipate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + CO2
Orthology
K15791  2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
Other DBs
RHEA: 12191

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG RCLASS (2)   
Gene (693)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (692)   
All databases (701)   

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