| Entry |
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| Name |
acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
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| Definition |
(S)-3-Hydroxy-3-methylglutaryl-CoA + CoA <=> Acetyl-CoA + H2O + Acetoacetyl-CoA
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| Equation |
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|
 |
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| Comment |
possibly two-step reaction (acetoacetyl-CoA-lyase, thioester-hydrolysing)
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| RPair |
| C00010_C00024 main | | C00332_C00356 main | | C00024_C00356 trans | | C00001_C00356 leave |
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| Enzyme |
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| Pathway |
| Synthesis and degradation of ketone bodies | | Valine, leucine and isoleucine degradation | | Butanoate metabolism | | Terpenoid backbone biosynthesis | | Metabolic pathways | | Biosynthesis of secondary metabolites |
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| Orthology |
| hydroxymethylglutaryl-CoA synthase [EC: 2.3.3.10] |
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