KEGG   REACTION: R02131
Entry
R02131                      Reaction                               
Name
steroid,NADPH-hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating)
Definition
Steroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxysteroid + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00377 + C03024 + C00007 <=> C03336 + C03161 + C00001
Comment
general reaction (see R02211, R03783, R04852 and R04853)
P-450 reductase (ec 1.6.2.4) is the acceptor and re-reduced by NADPH (see R08551)
Enzyme
1.14.14.19
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19
     R02131  Steroid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxysteroid + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.19
   R02131  Steroid <=> 17alpha-Hydroxysteroid
Other DBs
RHEA: 65763

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Ontology (2)   
   KEGG BRITE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
All databases (9)   

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