KEGG   REACTION: R02213
Entry
R02213                      Reaction                               
Name
progesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating)
Definition
Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycorticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00410 + C03024 + C00007 <=> C03205 + C03161 + C00001
Reaction class
RC00157  C00410_C03205
Enzyme
1.14.14.16
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16
     R02213  Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycorticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.16
   R02130  Steroid <=> 21-Hydroxysteroid
    R02213  Progesterone <=> 11-Deoxycorticosterone
Orthology
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Other DBs
RHEA: 50307

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (354)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (353)   
All databases (369)   

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