KEGG   REACTION: R02216Help
Entry
R02216                      Reaction                               

Name
Pregnenolone:NAD+ 3-oxidoreductase
Definition
Pregnenolone + NAD+ <=> Progesterone + NADH + H+
Equation
Comment
3beta-hydroxysteroid dehydrogenase/ Delta5-Delta4-isomerase
two-step reaction
RPair
C00003_C00004 cofac [RC:RC00001]
C00410_C01953 main [RC:RC00146]
Enzyme
1.1.1.145       5.3.3.1
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Orthology
K00070  
3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
K01822  
steroid delta-isomerase [EC:5.3.3.1]

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