KEGG   REACTION: R02442
Entry
R02442                      Reaction                               
Name
naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Definition
Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eriodictyol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00509 + C03024 + C00007 <=> C05631 + C03161 + C00001
Comment
flavonoid 3'-hydroxylase
flavonoid 3'-monooxygenase
first step of two-step reaction (see R02443, R02442+R04902)
Reaction class
RC00046  C00509_C05631
Enzyme
1.14.14.81      1.14.14.82
Pathway
rn00941  Flavonoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.81
     R02442  Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eriodictyol + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.82
     R02442  Naringenin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eriodictyol + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.81
   R07369  Flavanone <=> 3'-Hydroxyflavanone
    R02442  Naringenin <=> Eriodictyol
  1.14.14.82
   R03615  Flavonoid <=> 3'-Hydroxyflavonoid
    R02442  Naringenin <=> Eriodictyol
Orthology
K05280  flavonoid 3'-monooxygenase [EC:1.14.14.82]
K13083  flavonoid 3',5'-hydroxylase [EC:1.14.14.81]
Other DBs
RHEA: 61099

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (2)   
   KEGG RCLASS (1)   
Gene (530)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (528)   
All databases (545)   

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