KEGG   REACTION: R02535
Entry
R02535                      Reaction                               
Name
dopamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)
Definition
Dopamine + 2 Ascorbate + Oxygen <=> L-Noradrenaline + 2 Monodehydroascorbate + H2O
Equation
Reaction class
RC00741  C00547_C03758
Enzyme
Pathway
rn00350  Tyrosine metabolism
rn01100  Metabolic pathways
Module
M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.17  With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.17.1
     R02535  Dopamine + 2 Ascorbate + Oxygen <=> L-Noradrenaline + 2 Monodehydroascorbate + H2O
Orthology
K00503  dopamine beta-monooxygenase [EC:1.14.17.1]
Other DBs
RHEA: 19120

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