KEGG   REACTION: R02581
Entry
R02581                      Reaction                               
Name
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase;
prostaglandin F2alpha:NADP+ oxidoreductase
Definition
Prostaglandin F2alpha + NADP+ <=> Prostaglandin E2 + NADPH + H+
Equation
C00639 + C00006 <=> C00584 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00154  C00584_C00639
Enzyme
1.1.1.184       1.1.1.189
Pathway
rn00590  Arachidonic acid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.184
     R02581  Prostaglandin F2alpha + NADP+ <=> Prostaglandin E2 + NADPH + H+
    1.1.1.189
     R02581  Prostaglandin F2alpha + NADP+ <=> Prostaglandin E2 + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.184
   R03557  Secondary alcohol <=> Ketone
    R02581  Prostaglandin F2alpha <=> Prostaglandin E2
Orthology
K00079  carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00081  carbonyl reductase 2 [EC:1.1.1.184]
K00084  carbonyl reductase 3 [EC:1.1.1.184]
Other DBs
RHEA: 24511

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (2254)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (2251)   
All databases (2270)   

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