KEGG   REACTION: R02864
Entry
R02864                      Reaction                               
Name
S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
Definition
Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin
Equation
C00748 + 2 C00080 <=> C14818 + C05778
Comment
multifunctional enzyme: siroheme synthase: sirohydrochlorin ferrochelatase (R03194+R03947+R02864)
following after R03947
Reaction class
RC01012  C00748_C05778
Enzyme
4.99.1.4
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4
     R02864  Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin
Orthology
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02304  precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
K03794  sirohydrochlorin ferrochelatase [EC:4.99.1.4]
Other DBs
RHEA: 24363

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (4426)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (4423)   
All databases (4442)   

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