KEGG   REACTION: R03326
Entry
R03326                      Reaction                               
Name
17alpha-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating)
Definition
17alpha-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycortisol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C01176 + C03024 + C00007 <=> C05488 + C03161 + C00001
Reaction class
RC00157  C01176_C05488
Enzyme
1.14.14.16
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16
     R03326  17alpha-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycortisol + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.16
   R02130  Steroid <=> 21-Hydroxysteroid
    R03326  17alpha-Hydroxyprogesterone <=> 11-Deoxycortisol
Orthology
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Other DBs
RHEA: 50311

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (354)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (353)   
All databases (369)   

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