KEGG   REACTION: R03376
Entry
R03376                      Reaction                               
Name
[procollagen]-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)
Definition
Protein lysine + 2-Oxoglutarate + Oxygen <=> Procollagen 5-hydroxy-L-lysine + Succinate + CO2
Equation
C02188 + C00026 + C00007 <=> C01211 + C00042 + C00011
Reaction class
RC00709  C01211_C02188
Enzyme
1.14.11.4
Pathway
rn00310  Lysine degradation
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.4
     R03376  Protein lysine + 2-Oxoglutarate + Oxygen <=> Procollagen 5-hydroxy-L-lysine + Succinate + CO2
Orthology
K00473  procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [EC:1.14.11.4]
K13645  procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4]
K13646  lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66]
K13647  procollagen-lysine,2-oxoglutarate 5-dioxygenase, invertebrate [EC:1.14.11.4]
Other DBs
RHEA: 16572

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (1384)   
   KEGG ORTHOLOGY (4)   
   KEGG GENES (1380)   
All databases (1397)   

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