KEGG   REACTION: R03610
Entry
R03610                      Reaction                               
Name
calcidiol,adrenodoxin:oxygen oxidoreductase (1-hydroxylating)
Definition
Calcidiol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitriol + Oxidized adrenal ferredoxin + H2O
Equation
Reaction class
RC00723  C01561_C01673
Enzyme
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
Module
M00103  Cholecalciferol biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.18
     R03610  Calcidiol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitriol + Oxidized adrenal ferredoxin + H2O
Orthology
K07438  calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]
Other DBs
RHEA: 20576

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