KEGG   REACTION: R05127
Entry
R05127                      Reaction                               
Name
thebaine,2-oxoglutarate:oxygen oxidoreductase (3-O-demethylating)
Definition
Thebaine + 2-Oxoglutarate + Oxygen <=> Oripavine + Formaldehyde + Succinate + CO2
Equation
Reaction class
RC00392  C06173_C06175
RC01533  C00067_C06173
Enzyme
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00944  Morphine biosynthesis, (S)-reticuline => morphine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.32
     R05127  Thebaine + 2-Oxoglutarate + Oxygen <=> Oripavine + Formaldehyde + Succinate + CO2
Orthology
K14975  codeine 3-O-demethylase [EC:1.14.11.32]

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