KEGG   REACTION: R05188
Entry
R05188                      Reaction                               
Name
acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)
Definition
Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 2n H+ <=> Long-chain fatty acid + n CO2 + 2n NADP+ + (n+1) CoA + n H2O
Equation
C00024 + n C00083 + 2n C00005 + 2n C00080 <=> C00638 + n C00011 + 2n C00006 + (n+1) C00010 + n C00001
Comment
multi-step reaction (see map00061)
Reaction class
RC00001  C00005_C00006
RC00004  C00010_C00024  C00010_C00083
Enzyme
2.3.1.85
Pathway
rn00061  Fatty acid biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.85
     R05188  Acetyl-CoA + n Malonyl-CoA + 2n NADPH + 2n H+ <=> Long-chain fatty acid + n CO2 + 2n NADP+ + (n+1) CoA + n H2O
Orthology
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
Other DBs
RHEA: 14996

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (1556)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1555)   
All databases (1571)   

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