KEGG   REACTION: R06519
Entry
R06519                      Reaction                               
Name
dihydroceramide,ferrocytochrome b5:oxygen oxidoreductase (4,5-dehydrogenating)
Definition
Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Acylsphingosine + 2 Ferricytochrome b5 + 2 H2O
Equation
C12126 + 2 C00999 + C00007 + 2 C00080 <=> C00195 + 2 C00996 + 2 C00001
Reaction class
RC00824  C00195_C12126
Enzyme
1.14.19.17
Pathway
rn00600  Sphingolipid metabolism
rn01100  Metabolic pathways
Module
M00094  Ceramide biosynthesis
M00099  Sphingosine biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.17
     R06519  Dihydroceramide + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> N-Acylsphingosine + 2 Ferricytochrome b5 + 2 H2O
Orthology
K04712  sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
Other DBs
RHEA: 46547

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (1693)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1692)   
All databases (1709)   

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