KEGG   REACTION: R07079Help
Entry
R07079                      Reaction                               

Name
Benzpyrene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Benzo[a]pyrene + NADPH + Oxygen + H+ <=> Benzo[a]pyrene-9,10-oxide + NADP+ + H2O
Equation
Comment
CYP1A1, CYP1B1, CYP2C9, CYP3A4
RPair
C00005_C00006 cofac [RC:RC00001]
C00001_C00007 cofac
C00007_C14849 leave
C07535_C14849 main [RC:RC01445]
Enzyme
1.14.13.-       1.14.14.1
Pathway
Metabolism of xenobiotics by cytochrome P450
Orthology
K07408  
cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
K07410  
cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
K17689  
cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
K17719  
cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]

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