KEGG   REACTION: R07098
Entry
R07098                      Reaction                               
Name
trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Trichloroethene + NADPH + Oxygen + H+ <=> TCE epoxide + NADP+ + H2O
Equation
C06790 + C00005 + C00007 + C00080 <=> C11148 + C00006 + C00001
Comment
CYP2E1, CYP2F2/4, CYP2B1 (ec 1.14.14.1), CYP1A1/2
Soluble methane monooxygenase (ec 1.14.13.25)
NADH (ec 1.14.13.25, see R09141)
Reaction class
RC00001  C00005_C00006
RC01732  C06790_C11148
Enzyme
1.14.13.25      1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.25
     R07098  Trichloroethene + NADPH + Oxygen + H+ <=> TCE epoxide + NADP+ + H2O
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R07098  Trichloroethene + NADPH + Oxygen + H+ <=> TCE epoxide + NADP+ + H2O
    1.14.14.-
     R07098  Trichloroethene + NADPH + Oxygen + H+ <=> TCE epoxide + NADP+ + H2O
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG RCLASS (2)   
   UMBBD-RN (1)   
Gene (519)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (516)   
All databases (534)   

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