KEGG   REACTION: R07099
Entry
R07099                      Reaction                               
Name
trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Trichloroethene + NADPH + Oxygen + H+ <=> Chloral + NADP+ + H2O
Equation
Comment
CYP2E1, CYP2F2/4, CYP2B1, CYP1A1/2
Reaction class
RC00001  C00005_C00006
RC01733  C06790_C14866
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R07099  Trichloroethene + NADPH + Oxygen + H+ <=> Chloral + NADP+ + H2O
    1.14.14.-
     R07099  Trichloroethene + NADPH + Oxygen + H+ <=> Chloral + NADP+ + H2O
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]

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