KEGG   REACTION: R07372
Entry
R07372                      Reaction                               
Name
cholest-5-ene-3beta,26-diol,[NADPH---hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating)
Definition
Cholest-5-ene-3beta,26-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha,27-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C15610 + C03024 + C00007 <=> C06341 + C03161 + C00001
Reaction class
RC00524  C06341_C15610
Enzyme
1.14.14.23      1.14.14.29
Pathway
rn00120  Primary bile acid biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.23
     R07372  Cholest-5-ene-3beta,26-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha,27-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.29
     R07372  Cholest-5-ene-3beta,26-diol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 7alpha,27-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K00489  cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K07430  25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]
Other DBs
RHEA: 19044

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (2)   
   KEGG RCLASS (1)   
Gene (909)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (907)   
All databases (921)   

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