KEGG REACTION: R08160

REACTION: R08160

Entry

R08160 Reaction

Name

L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)

Definition

L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ <=> Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2

Equation

C00078 + 2 C00007 + 2 C00005 + 2 C00080 <=> C02937 + 3 C00001 + 2 C00006 + C00011

Comment

three-step reaction (see R09583+R09584+R09585)

RPair

RP00001	C00005_C00006 cofac
RP00013	C00001_C00007 cofac
RP05841	C00011_C00078 leave
RP13283	C00078_C02937 main
RP13284	C00007_C02937 leave

Enzyme

1.14.13.125

Pathway

rn00380	Tryptophan metabolism
rn00966	Glucosinolate biosynthesis
rn01110	Biosynthesis of secondary metabolites
rn01210	2-Oxocarboxylic acid metabolism

Orthology

K11812	cytochrome P450, family 79, subfamily B, polypeptide 2 (tryptophan N-monooxygenase) [EC:1.14.13.125]
K11813	cytochrome P450, family 79, subfamily B, polypeptide 3 (tryptophan N-monooxygenase) [EC:1.14.13.125]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (11)   
   KEGG PATHWAY (8)   
   KEGG MODULE (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
   KEGG RPAIR (5)   
   KEGG RCLASS (1)   
Gene (6)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (4)   
All databases (37)   

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