KEGG   REACTION: R08160Help
Entry
R08160                      Reaction                               

Name
L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)
Definition
L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ <=> Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2
Equation
C00078 + 2 C00007 + 2 C00005 + 2 C00080 <=> C02937 + 3 C00001 + 2 C00006 + C00011
Comment
three-step reaction (see R09583+R09584+R09585)
RPair
C00005_C00006 cofac [RC:RC00001]
C00001_C00007 cofac
C00011_C00078 leave
C00078_C02937 main [RC:RC02295]
C00007_C02937 leave
Enzyme
Pathway
Tryptophan metabolism
Glucosinolate biosynthesis
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Module
M00370  
Glucosinolate biosynthesis, tryptophan => glucobrassicin
Orthology
K11812  
tryptophan N-monooxygenase [EC:1.14.13.125]
K11813  
tryptophan N-monooxygenase [EC:1.14.13.125]

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