KEGG   REACTION: R08160
Entry
R08160                      Reaction                               
Name
L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C00078 + 2 C03024 + 2 C00007 <=> C02937 + 2 C03161 + C00011 + 3 C00001
Comment
three-step reaction (see R09583+R09584+R09585)
Reaction class
RC02295  C00078_C02937
Enzyme
1.14.14.156
Pathway
rn00380  Tryptophan metabolism
rn00966  Glucosinolate biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Module
M00370  Glucosinolate biosynthesis, tryptophan => glucobrassicin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.156
     R08160  L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Orthology
K11812  tryptophan N-monooxygenase [EC:1.14.14.156]
K11813  tryptophan N-monooxygenase [EC:1.14.14.156]
Other DBs
RHEA: 33282

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (48)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (46)   
All databases (69)   

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