KEGG   REACTION: R08518Help
Entry
R08518                      Reaction                               

Name
17alpha-hydroxyprogesterone,hydrogen-donor:oxygen oxidoreductase (side-chain-cleaving, acetate-formig)
Definition
17alpha-Hydroxyprogesterone + Reduced acceptor + Oxygen <=> Androstenedione + Acetate + Acceptor + H2O
Equation
Comment
17alpha-hydroxylase/17,20-lyase
P-450 reductase is acceptor and re-reduced by NADPH
RPair
C00001_C00007 cofac
C00280_C01176 main
C00007_C00033 leave
C00033_C01176 main
Enzyme
Pathway
Steroid hormone biosynthesis
Orthology
K00512  
steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone aldolase [EC:1.14.99.9 4.1.2.30]

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