KEGG   REACTION: R08727
Entry
R08727                      Reaction                               
Name
3beta-hydroxy-5-cholestenoate,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)
Definition
3beta-Hydroxy-5-cholestenoate + Oxygen + NADPH + H+ <=> 3beta,7alpha-Dihydroxy-5-cholestenoate + NADP+ + H2O
Equation
C17333 + C00007 + C00005 + C00080 <=> C17335 + C00006 + C00001
Reaction class
RC00001  C00005_C00006
RC00524  C17333_C17335
Enzyme
1.14.14.29
Pathway
rn00120  Primary bile acid biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.29
     R08727  3beta-Hydroxy-5-cholestenoate + Oxygen + NADPH + H+ <=> 3beta,7alpha-Dihydroxy-5-cholestenoate + NADP+ + H2O
Orthology
K07430  25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (415)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (414)   
All databases (428)   

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