KEGG   REACTION: R08838
Entry
R08838                      Reaction                               
Name
benzoate,NADPH:oxygen oxidoreductase (2-hydroxylating)
Definition
Benzoate + NADPH + Oxygen <=> Salicylate + NADP+ + H2O
Equation
C00180 + C00005 + C00007 <=> C00805 + C00006 + C00001
Comment
benzoic acid 2-hydroxylase (BA2H)
Reaction class
RC00001  C00005_C00006
RC00046  C00180_C00805
Enzyme
1.14.13.-
Pathway
rn00996  Biosynthesis of various alkaloids
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-
     R08838  Benzoate + NADPH + Oxygen <=> Salicylate + NADP+ + H2O
Reference
1  [PMID:7479795]
  Authors
Leon J, Shulaev V, Yalpani N, Lawton MA, Raskin I.
  Title
Benzoic acid 2-hydroxylase, a soluble oxygenase from tobacco, catalyzes salicylic acid biosynthesis.
  Journal
Proc Natl Acad Sci U S A 92:10413-7 (1995)
DOI:10.1073/pnas.92.22.10413

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG RCLASS (2)   
All databases (13)   

Download RDF
DBGET integrated database retrieval system