KEGG   REACTION: R08949
Entry
R08949                      Reaction                               
Name
11-deoxycorticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta,18-hydroxylating)
Definition
11-Deoxycorticosterone + 3 Reduced adrenal ferredoxin + 3 Oxygen <=> Aldosterone + 3 Oxidized adrenal ferredoxin + 4 H2O
Equation
C03205 + 3 C00662 + 3 C00007 <=> C01780 + 3 C00667 + 4 C00001
Comment
three-step reaction (see R03851+R03262+R03263)
Reaction class
RC02388  C01780_C03205
Enzyme
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4
     R08949  11-Deoxycorticosterone + 3 Reduced adrenal ferredoxin + 3 Oxygen <=> Aldosterone + 3 Oxidized adrenal ferredoxin + 4 H2O
Orthology
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]

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