KEGG   REACTION: R09549
Entry
R09549                      Reaction                               
Name
(+)-germacrene-A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
Definition
(+)-Germacrene A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacra-1(10),4,11(13)-trien-12-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C16141 + C03024 + C00007 <=> C19676 + C03161 + C00001
Comment
the first step of three-step reaction (see R12128, R09549+R12129+R12130)
Reaction class
RC01137  C16141_C19676
Enzyme
1.14.14.95
Pathway
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.95
     R09549  (+)-Germacrene A + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Germacra-1(10),4,11(13)-trien-12-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K15800  germacrene A oxidase [EC:1.14.14.95]
Other DBs
RHEA: 61311

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (9)   
All databases (23)   

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