KEGG   REACTION: R09575
Entry
R09575                      Reaction                               
Name
germacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
Definition
Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Costunolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C19678 + C03024 + C00007 <=> C09382 + C03161 + 2 C00001
Comment
two-step reaction (see R12131+R12132)
Reaction class
RC02572  C09382_C19678
Enzyme
1.14.14.150
Pathway
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.150
     R09575  Germacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Costunolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Orthology
K20561  costunolide synthase [EC:1.14.14.150]
Other DBs
RHEA: 28233

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (9)   
All databases (23)   

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