KEGG   REACTION: R10415
Entry
R10415                      Reaction                               
Name
(3S,5S)-carbapenam-3-carboxylate,2-oxoglutarate:oxygen oxidoreductase (dehydrating)
Definition
(3S,5S)-Carbapenam-3-carboxylic acid + 2-Oxoglutarate + Oxygen <=> (5R)-Carbapen-2-em-3-carboxylate + Succinate + CO2 + H2O
Equation
C17367 + C00026 + C00007 <=> C06669 + C00042 + C00011 + C00001
Reaction class
RC03174  C06669_C17367
Enzyme
1.14.20.3       1.14.20.-
Pathway
rn00332  Carbapenem biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00675  Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.20  With 2-oxoglutarate as one donor, and the other dehydrogenated
    1.14.20.3
     R10415  (3S,5S)-Carbapenam-3-carboxylic acid + 2-Oxoglutarate + Oxygen <=> (5R)-Carbapen-2-em-3-carboxylate + Succinate + CO2 + H2O
    1.14.20.-
     R10415  (3S,5S)-Carbapenam-3-carboxylic acid + 2-Oxoglutarate + Oxygen <=> (5R)-Carbapen-2-em-3-carboxylate + Succinate + CO2 + H2O
Orthology
K18315  (5R)-carbapenem-3-carboxylate synthase [EC:1.14.20.3]
K18562  2-oxoglutarate-dependent dioxygenase [EC:1.14.20.-]
Other DBs
RHEA: 36614

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (46)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (44)   
All databases (63)   

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