KEGG   Rattus norvegicus (rat): 24240Help
Entry
24240             CDS       T01003                                 

Gene name
Cad
Definition
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2)
Orthology
K11540  
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
rno  Rattus norvegicus (rat)
Pathway
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Metabolic pathways
Module
Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Nucleotide metabolism
   00240 Pyrimidine metabolism
    24240 (Cad)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    24240 (Cad)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     24240 (Cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     24240 (Cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     24240 (Cad)
Peptidases [BR:rno01002]
 Cysteine Peptidases
  Family C26: gamma-glutamyl hydrolase family
   24240 (Cad)
 Metallo Peptidases
  Family M38: beta-aspartyl dipeptidase family
   24240 (Cad)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
Position
6q14
AA seq 2225 aa AA seqDB search
MAALVLEDGSVLQGRPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPSDEEDEFGLSKWFESSEIHVAGLVVGECCPTPSHWSATCTLHEWLQQHGIPGLQGVD
TRELTKKLREQGSLLGKLVQKGTEPSALPFVDPNARPLAPEVSIKTPRVFNAGGAPRIFA
VDCGLKYNQIRCLCQLGAEVTVVPWNHELDSRKYDGLFLSNGPGDPASYPGVVSTLNRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVD
ADSLPAGWAPLFTNANDCSNEGIVHDNLPFFSVQFHPEHRAGPSDMELLFDVFLETVRDT
VAGNAEGRTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDVELETPTDKRIFVVAAALWAGYSVERLYELTRIDCWFLHRM
KRIVTHAKLLEQHRGRPLPQDLLHQAKCLGFSDKQIALAVLSTELVVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVESVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPSHLPIVAHAERQSVAAVLMVAQLTRRSVHICHVARKEE
ILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVI
DCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPLQEDTYVEVDLEHEWTVPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQPPPPTPTTTEITTTPERPRRVIPGLPDGRFHLPPRIHRASD
PGLPAEEPKEKPPRKVAESELIGTPDGPCYPVPPVPRQASPQNLGSSGLLHPQMSPLLHS
LVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPSSVWDFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSSQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq 6678 nt NT seq  +upstreamnt  +downstreamnt
atggcggccctggtgttggaggacgggtcggtgctgcagggccggcccttcggggccgct
gtgtcgactgctggggaagtggtgtttcagaccggcatggtcggctacccggaggccctc
actgacccttcctacaaagctcagatcctagtgctaacgtaccctctcatcggcaactac
ggtattccctcagatgaagaggacgagttcggcctgagcaagtggtttgaatcctcggag
atccatgtggcaggtctggtggttggggaatgctgtcccacgcccagccactggagtgcc
acctgcaccctgcatgagtggctgcaacagcatggcatccccggcctgcaaggagtggac
actcgggagctgactaagaagttgcgggaacaagggtctcttttggggaagctggtccag
aaagggacagagccttcagccctgccatttgtggaccccaatgccaggcccctggcacca
gaggtctctattaagaccccacgggtattcaatgcggggggtgcccctcggatctttgct
gtagactgtggcctcaagtacaatcagatccgatgtctctgccagcttggggctgaggtt
accgtggtaccctggaaccatgaattagacagtcggaaatatgacggtctcttcctaagt
aatggacctggtgatcctgcctcctatcctggtgtggtgtccacactgaatcgagtctta
tctgagcctaatccccgacctgtgtttggaatctgccttggacaccagctattggcttta
gccattggggccaaaacttacaagatgagatacggaaaccgaggccacaaccagccctgt
ttactggtgggtactgggcgctgctttctgacctcccagaatcacgggtttgccgtggac
gcggattcgctgccagcaggctgggctcctctatttaccaacgccaatgactgttccaac
gaaggcattgtacacgacaatctgcccttcttcagcgtccagtttcaccccgagcaccgg
gctggcccttcagatatggagctactcttcgatgtgtttctagaaaccgtgagagatact
gtagctgggaacgccgagggccggacagtaagagaacgtttggctcagcgcctctgtccc
cctgagcttcccattcctggttctgggctcccaccaccacgaaaagttctgatcctgggc
tcggggggcctctccattggccaggctggagaatttgactactcgggctctcaggcaatt
aaagccctaaaggaggagaacatccaaacattactgatcaaccccaacattgccacagtg
cagacttctcaggggctggcagacaaggtctatttccttcccataacacctcactacgta
acccaggtgattcgtaatgaacgcccagatggtatattactgactttcgggggtcagaca
gccctgaactgcggtgtggagctgaccaaagctggggtactagctcggtatggggtccgg
gtcttgggtacacctgtggagaccattgaactgactgaggaccggcgagcctttgctgcc
agaatggctgagattggagagcacgttgcccccagtgaagctgcaaattctcttgaacag
gctcaggcagctgccgagcggctaggctaccctgtgctggtgcgagcagcctttgccctg
ggtggtcttggttctggctttgcttccaccaaagaggaactctcagctcttgtggctcca
gcctttgcccataccagccaggtgctgatagacaagtctctgaagggctggaaggagatt
gaatatgaggtggtgagagatgcctatggcaactgcgtaacggtatgtaacatggagaac
ttagacccactgggcatccatacgggggagtccatagtggtggctccaagccagacactg
aatgacagagagtaccagcttctgcggcggacagctatcaaggtcacccagcacctgggg
attgttggggagtgcaatgtgcagtatgccttgaaccccgagtctgagcagtattacatc
attgaagtaaatgccaggctctcccgaagctctgccctggccagtaaggccacaggctat
ccactagcctatgtggcagccaagctagcattgggcattcccctgccagagctcagaaac
tctgttacggggggaacagcagcctttgagcccagcctggactactgcgtggtaaagatt
cctcgctgggacctcagcaagttcctgcgtgtcagtaccaagattgggagctgcatgaag
agtgttggtgaagtcatgggcatcgggcgttcctttgaggaggccttccaaaaggccctg
cgcatggtagacgagaactgtgtaggcttcgaccatacagtgaagccagtcagcgacgtg
gagctggagacgccgacggataagcggatctttgtggtggctgctgctctgtgggctggc
tactctgtggagcgcctctacgagctcacccgcatcgactgctggttcctgcaccggatg
aagcgcattgtgacccacgccaagttgctggaacaacaccgtggacggcccttaccccaa
gacctgctgcaccaggccaagtgcctcggcttctcagacaagcaaattgctcttgcagtc
ctgagcacagagctggttgttcggaagctgcgtcaggaactggggatctgcccagcagtg
aagcagatcgacacagttgcagctgagtggccagcccagacaaattacctgtacctgaca
tactggggcaacacccatgacctcgactttcggacacctcacgtcctggtccttggctct
ggcgtctaccggatcggctccagcgttgagtttgattggtgtgctgtgggctgcatccag
cagctccggaagatgggttataagaccatcatggtgaactacaacccagagacagtcagc
accgactatgatatgtgtgaccgactctactttgatgagatctcttttgaggtggtgatg
gacatctatgagttagaaaaccccgaaggtgtgattctgtccatgggcgggcagctgccc
aacaacatggctatggctttgcatcggcagcagtgccgagtgctgggcacctcccccgaa
gccatcgactcagccgagaaccggttcaagttctcccggctcctagataccattggtatc
agccagcctcagtggcgagagctcagtgacctcgagtccgctcgccagttctgccagacc
gttgggtacccctgcgtagtgcgtccctcctatgtgctgagtggtgctgctatgaacgtg
gcctacactgatggggacctggagcgcttcctgagcagtgcagctgctgtctctaaggag
caccctgtggtcatctccaaattcattcaggaggcaaaggagattgatgtagatgctgtg
gcctgtgacggcatcgtgtcggctattgccatctctgagcacgtggagaatgcaggtgtg
cattcaggggatgccacgctggtgacccccccacaagacatcacccccaaaactctggag
cggatcaaagccattgtgcatgctgtgggccaggagctacaggtcacggggcccttcaat
ctgcagctcattgccaaggacgaccagctgaaggtcattgaatgtaacgtgcgggtgtcg
cgctccttcccgttcgtgtccaagacacttggtgtcgacctcgtagccttggccacaagg
atcatcatgggggagaaagtagagtccgtggggctcatgactggctctggagtcgtggga
gtaaaggtacctcagttctccttctcacgcttggccggtgctgacgtggtcctgggtgtg
gagatgaccagtactggagaggtggctggcttcggagagagccgttgtgaagcctacctc
aaagccatgctcagcactggctttaagatcccaaagaagaacatcctgctgaccattggc
agctacaagaataaaagtgagctgctcccaactgtgcggttgctggagagcctgggctac
agtctgtatgccagcttgggaactgccgacttctacaccgagcacggcgtcaaggtaaca
gctgtggactggcactttgaagaggctgtggatggtgagtgcccaccacaacggagcatc
ttggatcagctggccgagaatcactttgagctggtgattaacctgtcgatgcgcggggct
gggggtcggcgtctttcctccttcgttaccaagggctaccgcacccggcgtctggccgcg
gatttctccgtgcctctcatcattgatatcaagtgcaccaaactcttcgtggaggcccta
ggccagatcgggccagcccctcctttgaaagtccacgttgactgcatgacctcccagaag
ctagtgcgcctgcctggattgattgatgtccacgtgcaccttcgggaaccaggtgggact
cacaaagaggactttgcctcaggcacagctgccgccttggctgggggcgtcaccatggtt
tgtgctatgcctaatacccggccccccatcattgatgccccagctctggcgcttgcccag
aagctggcagaggctggcgcccgctgtgactttaccctcttcctcggagcctcatctgaa
aatgcagggactctgggtgctgtggctgggtctgcagcaggcctgaagctctacctcaat
gagaccttctctgagctacggctggacagtgtggcccagtggatggagcattttgaaacc
tggccttcccacctccccattgtggcccacgcagagcggcagagtgtcgctgcggtcctc
atggtggctcagctgacacggcgttcagtgcacatatgtcatgtggctcggaaggaagag
atcctgctgattaaaactgcaaaggcacaggggctgccagtgacgtgtgaggtcgcacct
caccacctgttcctaaaccgggaagacttggagcgcctgggacctgggaagggagaggtc
cgccctgagctgggttcccgagaggatatggaagccctgtgggagaatatggcggtcatc
gactgttttgcctcagaccacgctccccataccttggaagagaagtgtgggcctaagcct
ccaccaggctttccaggactagagaccatgttgccgctgctactgacagctgtgagtgaa
ggccgcctcagtctggatgacctgctacagcgattgcaccacaaccctcggcggatcttc
cacctgcctctccaggaggacacctatgtagaggtggatctggagcatgagtggacggtc
cccagccacatgcccttctctaaagcccactggaccccatttgaaggtcagaaggtgaag
ggcaccgtgcgccgtgtggtcttgagaggggaggtcgcctatattgatggacaggtgctg
gtacccccgggctatggacaagatgtacggaagtggcctcagggggctgttcctcagcct
cctcctccaactcctactaccactgaaataaccacgacacctgagagaccacgccgagtc
atcccaggccttcctgatggccgattccacctgccacctcgaatccaccgggcctctgac
ccagggctgccagctgaggaacccaaagagaagccacccaggaaggtagcagaatcagag
ctgataggaacccctgatggcccctgctaccctgtaccaccagtacctagacaggcatca
ccacagaatctaggatcttctggcctgctgcacccccagatgtcacctttactgcactcc
ctagtgggccaacacatcctgtctgtcaagcagttcactaaggatcagatgtctcatctg
ttcaacgtggcgcacacactacggatgatggtgcagaaagaacggagcctcgacatccta
aaggggaaggtcatggcctctatgttctacgaggtgagcacccgcaccagtagctccttc
gcagcagccatggcccggctcgggggtgccgttctcagcttctctgaagccacgtcctcc
gtccagaagggcgaatccctcgccgactcggtgcagaccatgagttgctatgctgatgtt
gttgtactccgtcaccctcagcctggagctgtggagctggcggccaagcactgtcgaaga
ccagtgatcaatgctggagatggagttggggagcaccccactcaggccctgctggacatc
ttcaccattcgagaagagcttgggactgtcaatggcatgacgatcactatggtaggcgac
ctgaagcatggacgcacagtgcactccctggcctgcctgctcacccagtaccgtgtgagc
ctacgctacgtggcacctcccagcctgcgcatgccatccagcgtgtgggactttgtggcc
tcccgaggcaccaagcaggaggagttcgagagcatcgaggaggcgctgccagacactgac
gtgctctacatgactcggatccagaaagaacgatttggctcttcccaggaatatgaagct
tgctttggtcagttcatcctcactcctcacatcatgacccgggccaagaaaaagatggtg
gtgatgcacccaatgcctcgtgtcaatgagataagcgtggaggtggactcggaccccaga
gcagcctatttccgccaagctgagaacggcatgtacatccgcatggctctgcttgccacc
gtgctaggccgtttttag

DBGET integrated database retrieval system