KEGG   Rattus norvegicus (rat): 24240
Entry
24240             CDS       T01003                                 
Symbol
Cad
Name
(RefSeq) CAD protein
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00240  Pyrimidine metabolism
rno00250  Alanine, aspartate and glutamate metabolism
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
Module
rno_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    24240 (Cad)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    24240 (Cad)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    24240 (Cad)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     24240 (Cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     24240 (Cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     24240 (Cad)
Peptidases and inhibitors [BR:rno01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   24240 (Cad)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   24240 (Cad)
SSDB
Motif
Pfam: CPSase_L_D2 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp MGS Dala_Dala_lig_C ATPgrasp_Ter Amidohydro_1 ATP-grasp_3 GARS_A Peptidase_C26
Other DBs
NCBI-GeneID: 24240
NCBI-ProteinID: NP_001099180
RGD: 1588606
Ensembl: ENSRNOG00000026474
Position
6:complement(31012091..31035098)
AA seq 2225 aa
MAALVLEDGSVLQGRPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPSDEEDEFGLSKWFESSEIHVAGLVVGECCPTPSHWSATCTLHEWLQQHGIPGLQGVD
TRELTKKLREQGSLLGKLVQKGTEPSALPFVDPNARPLAPEVSIKTPRVFNAGGAPRIFA
VDCGLKYNQIRCLCQLGAEVTVVPWNHELDSRKYDGLFLSNGPGDPASYPGVVSTLNRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVD
ADSLPAGWAPLFTNANDCSNEGIVHDNLPFFSVQFHPEHRAGPSDMELLFDVFLETVRDT
VAGNAEGRTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDVELETPTDKRIFVVAAALWAGYSVERLYELTRIDCWFLHRM
KRIVTHAKLLEQHRGRPLPQDLLHQAKCLGFSDKQIALAVLSTELVVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVESVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPSHLPIVAHAERQSVAAVLMVAQLTRRSVHICHVARKEE
ILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVI
DCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPLQEDTYVEVDLEHEWTVPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQPPPPTPTTTEITTTPERPRRVIPGLPDGRFHLPPRIHRASD
PGLPAEEPKEKPPRKVAESELIGTPDGPCYPVPPVPRQASPQNLGSSGLLHPQMSPLLHS
LVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPSSVWDFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSSQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq 6678 nt   +upstreamnt  +downstreamnt
atggcggccctggtgttggaggacgggtcggtgctgcagggccggcccttcggggccgct
gtgtcgactgctggggaagtggtgtttcagaccggcatggtcggctacccggaggccctc
actgacccttcctacaaagctcagatcctagtgctaacgtaccctctcatcggcaactac
ggtattccctcagatgaagaggacgagttcggcctgagcaagtggtttgaatcctcggag
atccatgtggcaggtctggtggttggggaatgctgtcccacgcccagccactggagtgcc
acctgcaccctgcatgagtggctgcaacagcatggcatccccggcctgcaaggagtggac
actcgggagctgactaagaagttgcgggaacaagggtctcttttggggaagctggtccag
aaagggacagagccttcagccctgccatttgtggaccccaatgccaggcccctggcacca
gaggtctctattaagaccccacgggtattcaatgcggggggtgcccctcggatctttgct
gtagactgtggcctcaagtacaatcagatccgatgtctctgccagcttggggctgaggtt
accgtggtaccctggaaccatgaattagacagtcggaaatatgacggtctcttcctaagt
aatggacctggtgatcctgcctcctatcctggtgtggtgtccacactgaatcgagtctta
tctgagcctaatccccgacctgtgtttggaatctgccttggacaccagctattggcttta
gccattggggccaaaacttacaagatgagatacggaaaccgaggccacaaccagccctgt
ttactggtgggtactgggcgctgctttctgacctcccagaatcacgggtttgccgtggac
gcggattcgctgccagcaggctgggctcctctatttaccaacgccaatgactgttccaac
gaaggcattgtacacgacaatctgcccttcttcagcgtccagtttcaccccgagcaccgg
gctggcccttcagatatggagctactcttcgatgtgtttctagaaaccgtgagagatact
gtagctgggaacgccgagggccggacagtaagagaacgtttggctcagcgcctctgtccc
cctgagcttcccattcctggttctgggctcccaccaccacgaaaagttctgatcctgggc
tcggggggcctctccattggccaggctggagaatttgactactcgggctctcaggcaatt
aaagccctaaaggaggagaacatccaaacattactgatcaaccccaacattgccacagtg
cagacttctcaggggctggcagacaaggtctatttccttcccataacacctcactacgta
acccaggtgattcgtaatgaacgcccagatggtatattactgactttcgggggtcagaca
gccctgaactgcggtgtggagctgaccaaagctggggtactagctcggtatggggtccgg
gtcttgggtacacctgtggagaccattgaactgactgaggaccggcgagcctttgctgcc
agaatggctgagattggagagcacgttgcccccagtgaagctgcaaattctcttgaacag
gctcaggcagctgccgagcggctaggctaccctgtgctggtgcgagcagcctttgccctg
ggtggtcttggttctggctttgcttccaccaaagaggaactctcagctcttgtggctcca
gcctttgcccataccagccaggtgctgatagacaagtctctgaagggctggaaggagatt
gaatatgaggtggtgagagatgcctatggcaactgcgtaacggtatgtaacatggagaac
ttagacccactgggcatccatacgggggagtccatagtggtggctccaagccagacactg
aatgacagagagtaccagcttctgcggcggacagctatcaaggtcacccagcacctgggg
attgttggggagtgcaatgtgcagtatgccttgaaccccgagtctgagcagtattacatc
attgaagtaaatgccaggctctcccgaagctctgccctggccagtaaggccacaggctat
ccactagcctatgtggcagccaagctagcattgggcattcccctgccagagctcagaaac
tctgttacggggggaacagcagcctttgagcccagcctggactactgcgtggtaaagatt
cctcgctgggacctcagcaagttcctgcgtgtcagtaccaagattgggagctgcatgaag
agtgttggtgaagtcatgggcatcgggcgttcctttgaggaggccttccaaaaggccctg
cgcatggtagacgagaactgtgtaggcttcgaccatacagtgaagccagtcagcgacgtg
gagctggagacgccgacggataagcggatctttgtggtggctgctgctctgtgggctggc
tactctgtggagcgcctctacgagctcacccgcatcgactgctggttcctgcaccggatg
aagcgcattgtgacccacgccaagttgctggaacaacaccgtggacggcccttaccccaa
gacctgctgcaccaggccaagtgcctcggcttctcagacaagcaaattgctcttgcagtc
ctgagcacagagctggttgttcggaagctgcgtcaggaactggggatctgcccagcagtg
aagcagatcgacacagttgcagctgagtggccagcccagacaaattacctgtacctgaca
tactggggcaacacccatgacctcgactttcggacacctcacgtcctggtccttggctct
ggcgtctaccggatcggctccagcgttgagtttgattggtgtgctgtgggctgcatccag
cagctccggaagatgggttataagaccatcatggtgaactacaacccagagacagtcagc
accgactatgatatgtgtgaccgactctactttgatgagatctcttttgaggtggtgatg
gacatctatgagttagaaaaccccgaaggtgtgattctgtccatgggcgggcagctgccc
aacaacatggctatggctttgcatcggcagcagtgccgagtgctgggcacctcccccgaa
gccatcgactcagccgagaaccggttcaagttctcccggctcctagataccattggtatc
agccagcctcagtggcgagagctcagtgacctcgagtccgctcgccagttctgccagacc
gttgggtacccctgcgtagtgcgtccctcctatgtgctgagtggtgctgctatgaacgtg
gcctacactgatggggacctggagcgcttcctgagcagtgcagctgctgtctctaaggag
caccctgtggtcatctccaaattcattcaggaggcaaaggagattgatgtagatgctgtg
gcctgtgacggcatcgtgtcggctattgccatctctgagcacgtggagaatgcaggtgtg
cattcaggggatgccacgctggtgacccccccacaagacatcacccccaaaactctggag
cggatcaaagccattgtgcatgctgtgggccaggagctacaggtcacggggcccttcaat
ctgcagctcattgccaaggacgaccagctgaaggtcattgaatgtaacgtgcgggtgtcg
cgctccttcccgttcgtgtccaagacacttggtgtcgacctcgtagccttggccacaagg
atcatcatgggggagaaagtagagtccgtggggctcatgactggctctggagtcgtggga
gtaaaggtacctcagttctccttctcacgcttggccggtgctgacgtggtcctgggtgtg
gagatgaccagtactggagaggtggctggcttcggagagagccgttgtgaagcctacctc
aaagccatgctcagcactggctttaagatcccaaagaagaacatcctgctgaccattggc
agctacaagaataaaagtgagctgctcccaactgtgcggttgctggagagcctgggctac
agtctgtatgccagcttgggaactgccgacttctacaccgagcacggcgtcaaggtaaca
gctgtggactggcactttgaagaggctgtggatggtgagtgcccaccacaacggagcatc
ttggatcagctggccgagaatcactttgagctggtgattaacctgtcgatgcgcggggct
gggggtcggcgtctttcctccttcgttaccaagggctaccgcacccggcgtctggccgcg
gatttctccgtgcctctcatcattgatatcaagtgcaccaaactcttcgtggaggcccta
ggccagatcgggccagcccctcctttgaaagtccacgttgactgcatgacctcccagaag
ctagtgcgcctgcctggattgattgatgtccacgtgcaccttcgggaaccaggtgggact
cacaaagaggactttgcctcaggcacagctgccgccttggctgggggcgtcaccatggtt
tgtgctatgcctaatacccggccccccatcattgatgccccagctctggcgcttgcccag
aagctggcagaggctggcgcccgctgtgactttaccctcttcctcggagcctcatctgaa
aatgcagggactctgggtgctgtggctgggtctgcagcaggcctgaagctctacctcaat
gagaccttctctgagctacggctggacagtgtggcccagtggatggagcattttgaaacc
tggccttcccacctccccattgtggcccacgcagagcggcagagtgtcgctgcggtcctc
atggtggctcagctgacacggcgttcagtgcacatatgtcatgtggctcggaaggaagag
atcctgctgattaaaactgcaaaggcacaggggctgccagtgacgtgtgaggtcgcacct
caccacctgttcctaaaccgggaagacttggagcgcctgggacctgggaagggagaggtc
cgccctgagctgggttcccgagaggatatggaagccctgtgggagaatatggcggtcatc
gactgttttgcctcagaccacgctccccataccttggaagagaagtgtgggcctaagcct
ccaccaggctttccaggactagagaccatgttgccgctgctactgacagctgtgagtgaa
ggccgcctcagtctggatgacctgctacagcgattgcaccacaaccctcggcggatcttc
cacctgcctctccaggaggacacctatgtagaggtggatctggagcatgagtggacggtc
cccagccacatgcccttctctaaagcccactggaccccatttgaaggtcagaaggtgaag
ggcaccgtgcgccgtgtggtcttgagaggggaggtcgcctatattgatggacaggtgctg
gtacccccgggctatggacaagatgtacggaagtggcctcagggggctgttcctcagcct
cctcctccaactcctactaccactgaaataaccacgacacctgagagaccacgccgagtc
atcccaggccttcctgatggccgattccacctgccacctcgaatccaccgggcctctgac
ccagggctgccagctgaggaacccaaagagaagccacccaggaaggtagcagaatcagag
ctgataggaacccctgatggcccctgctaccctgtaccaccagtacctagacaggcatca
ccacagaatctaggatcttctggcctgctgcacccccagatgtcacctttactgcactcc
ctagtgggccaacacatcctgtctgtcaagcagttcactaaggatcagatgtctcatctg
ttcaacgtggcgcacacactacggatgatggtgcagaaagaacggagcctcgacatccta
aaggggaaggtcatggcctctatgttctacgaggtgagcacccgcaccagtagctccttc
gcagcagccatggcccggctcgggggtgccgttctcagcttctctgaagccacgtcctcc
gtccagaagggcgaatccctcgccgactcggtgcagaccatgagttgctatgctgatgtt
gttgtactccgtcaccctcagcctggagctgtggagctggcggccaagcactgtcgaaga
ccagtgatcaatgctggagatggagttggggagcaccccactcaggccctgctggacatc
ttcaccattcgagaagagcttgggactgtcaatggcatgacgatcactatggtaggcgac
ctgaagcatggacgcacagtgcactccctggcctgcctgctcacccagtaccgtgtgagc
ctacgctacgtggcacctcccagcctgcgcatgccatccagcgtgtgggactttgtggcc
tcccgaggcaccaagcaggaggagttcgagagcatcgaggaggcgctgccagacactgac
gtgctctacatgactcggatccagaaagaacgatttggctcttcccaggaatatgaagct
tgctttggtcagttcatcctcactcctcacatcatgacccgggccaagaaaaagatggtg
gtgatgcacccaatgcctcgtgtcaatgagataagcgtggaggtggactcggaccccaga
gcagcctatttccgccaagctgagaacggcatgtacatccgcatggctctgcttgccacc
gtgctaggccgtttttag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (10)   
   KEGG ENZYME (3)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (14)   
   Pfam (14)   
All databases (57)   

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