KEGG   Rattus norvegicus (rat): 29337Help
Entry
29337             CDS       T01003                                 

Gene name
Plcg2
Definition
phospholipase C, gamma 2 (EC:3.1.4.11)
Orthology
K05859  
phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
rno  Rattus norvegicus (rat)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Osteoclast differentiation
Natural killer cell mediated cytotoxicity
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:rno00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:rno04014]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:rno04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:rno04370]
Environmental Information Processing; Signal transduction; NF-kappa B signaling pathway [PATH:rno04064]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:rno04066]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:rno04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:rno04070]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:rno04650]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:rno04662]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:rno04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:rno04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:rno04670]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:rno04919]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:rno04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:rno04750]
Organismal Systems; Development; Osteoclast differentiation [PATH:rno04380]
Human Diseases; Cancers; Pathways in cancer [PATH:rno05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:rno05206]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:rno05205]
Human Diseases; Cancers; Glioma [PATH:rno05214]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:rno05223]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:rno05169]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
19q12
AA seq 1265 aa AA seqDB search
MTTMVNVDTLPEYEKSQIKRALELGTVMTVFSARKSTPERRTVQMIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRHKADCCFTIFYGTQFVLSTLSLATDSKEDAV
KWLSGLKILHQEAMNASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGI
KFLKDKLVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKV
FKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKTQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEDPVQDTPPTELHFGEKWFHKKVESR
TSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYY
LTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDML
MRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVE
TKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
MQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFLVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLRLYQEKCNRRLREKRVSN
SRFYS
NT seq 3798 nt NT seq  +upstreamnt  +downstreamnt
atgaccaccatggtcaacgtggacacccttccagaatatgagaagagtcagatcaagaga
gccctggagctagggacggtgatgaccgtattcagtgcccgcaaatccaccccagagcgg
aggacagtacagatgatcatggagacccggcaggtggcatggagcaagacagcagataag
atcgaaggcttcttggacatcatggaaataaaggaaatccggccagggaagaactccaag
gactttgagcgagccaaggctgtccgtcacaaggcagactgctgcttcaccatcttctac
ggcacccagttcgtgctcagcactctcagtctggcaaccgactcaaaggaggatgcagtg
aagtggctctctggcttgaagatcttacaccaggaagcgatgaacgcatccactcccaca
atgattgagagttggctgcggaaacagatttattcagtagatcaaacccgaagaaacagc
atcagcctccgggagctgaagaccatcttgcccctggtcaacttcaaagtgagcggcatc
aagttcctcaaggacaagctggtggaaattggcgcccagaaagatgagctcagttttgaa
cagttccatctcttctataaaaaactcatgtttgagcagcagaagtcgatacttgacgaa
ttcaaaaaagactcctccgtgttcatcctagggaacacagaccggcctgatgcctcagcc
gtctacctgcaagacttccagaggtttcttttacatgaacagcaggagctatgggctcag
gatctgaacaaagtccgggagcggatgaccaagtttatcgatgacacaatgagggagacc
gcagagcccttcttgtttgtggatgagttcctcacgtatctgttctcacgggagaacagc
atctgggacgagaagtacgatgccgtggacatgcaggacatgaacaaccccttgtcccat
tactggatctcctcttcccacaacacgtacctcactggagaccagctgcgtagcgagtcc
tccacggaagcgtatatccgctgtctgcgtgctggttgtcgctgcatcgagttggattgc
tgggatgggcctgacgggaaacccataatctatcacggttggacacggaccaccaagatc
aagtttgatgatgttgttcaggccatccgggatcatgcctttgttacctccagctttccc
gtgattctgtctatcgaggagcactgcagtgtggagcagcaacgtcacatggccaaggtc
ttcaaggaagtgttaggagacctgctgttgacgaagcccacggaggccagtgctgaccag
ctgccctcacccagccagcttcgtgagaagatcattatcaagcataagaagctgggcccc
cgaggtgatgtcgatgtcaatgtggaggacaagaaagatgagcacaagacccagggcgag
ctgtatatgtgggactccatcgaccagaaatggactcgccactactgtgctattgcggac
gccaagctgtccttcagtgacgacattgaacagactgtggaagaggatccggtccaggac
actccccccacggagctacattttggggagaaatggttccataagaaggtggagagcagg
accagtgcggagaagctgctgcaggagtactgtgccgagactggggccaaggatggcacc
ttcctggtgcgggagagcgagaccttccccaacgactacacactctccttctggcggtct
ggccgggtgcagcactgccgaatccggtctaccatggagggtggggtcatgaagtactac
ctgactgacaacctcacgttcaacagcatctacgccctcatccagcactaccgggaggca
cacctgcgctgtgcggagttcgagctgcggctcacagacccggtgcccaaccccaaccca
catgagtccaagccgtggtactatgacaggctgagcaggggggaagcagaggacatgttg
atgcggattccccgagatggagccttcctcattcggaagcgggaggggaccgactcttac
gccatcaccttcagggccaggggcaaggtgaaacattgccgtatcaaccgggacggacgt
cactttgtgctggggacctctgcctactttgagagcctggtggagctcgtcagctactat
gagaagcacgcactctaccgcaagatgaggcttcgctaccccgtgaccccggagctcctg
gaacgatataatatggaaagagacatcaactctctctatgacgtcagcaggatgtatgtg
gacccaagtgagatcaacccttccatgcctcagaggactgtgaaagcactctatgactac
aaagccaagcgcagcgatgagctgaccttctgccgaggtgccctcatccacaacgtctcc
aaggagccgggaggatggtggaaaggggactatgggacccggatccagcagtatttccca
tctaactacgttgaagatatctcggcaggcgatgctgaggagatggaaaagcagattatt
gaagacaaccccctcgggtctctctgcagaggcatattggatcttaatacctacaatgtg
gtgaaggccccccaggggaaaaaccagaaagccttcgtctttatcctggagcctaagaaa
cagggggaccctcctgtggagttcgcgactgaccgtgtggaggaactgtttgagtggttt
cagagtatacgagagatcacttggaagatcgacaccaaggagaacaacatgaagtactgg
gagaggaatcagtccattgctattgagctctctgacttggttgtgtactgcaagccgact
agcaaaaccaaggaccatttggaaaatcctgacttccgggaaattcgctcttttgtggag
acaaaggcagacagcattgtcaggcaaaagcccgtggatctattgcggtacaaccagaag
ggcctgacccgtgtctaccccaagggacagagagttgactcttccaactacgaccccttc
cgtctgtggctgtgtggctcccagatggtggcgctcaatttccagactccagacaagtac
atgcagatgaaccatgcattgttttcgctcaatgggcggacaggttacgtcctgcagccc
gagagcatgcggtctgagaagtatgacccgatgcccccggagtcccagaggaagatcctg
atgacactcactgtcaaggttcttggtgcacgccacctccctaaactagggcggagtatc
gcctgtccctttgtagaggtggaaatctgtggggccgagtatgacagcaacaaattcaag
acgacggttgtgaatgacaacggtctcagccctgtctgggctccaactcaggagaaggtg
acatttgaaatttatgacccaaaccttgcgttcctacgctttctggtctacgaagaagac
atgttcagtgaccccaacttcctggctcatgccacataccccattaaaggcatcaaatca
ggatttagatcagtccctctgaagaacgggtacagtgaagacatcgagctggcatccctc
ctggttttctgtgagatgcggccagtcctggagagtgaagaagaactctattcctcctgt
cgccagctgcggaggcggcaggaagagctcaacaaccagctcttcctgtatgacacacac
cagaacctgcgaggagccaaccgggatgccctggtgaaggagttcaatgttaacgagaat
cagctgcggctgtaccaggagaagtgtaaccggaggctgagagagaagagagtgagtaac
agcaggttctactcctag

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