KEGG   Rattus norvegicus (rat): 309419
Entry
309419            CDS       T01003                                 
Symbol
Pip5k1b
Name
(RefSeq) phosphatidylinositol 4-phosphate 5-kinase type-1 beta
  KO
K00889  1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00562  Inositol phosphate metabolism
rno01100  Metabolic pathways
rno04070  Phosphatidylinositol signaling system
rno04072  Phospholipase D signaling pathway
rno04144  Endocytosis
rno04510  Focal adhesion
rno04666  Fc gamma R-mediated phagocytosis
rno04810  Regulation of actin cytoskeleton
rno05135  Yersinia infection
rno05231  Choline metabolism in cancer
Module
rno_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    309419 (Pip5k1b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    309419 (Pip5k1b)
   04072 Phospholipase D signaling pathway
    309419 (Pip5k1b)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    309419 (Pip5k1b)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    309419 (Pip5k1b)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    309419 (Pip5k1b)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    309419 (Pip5k1b)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    309419 (Pip5k1b)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    309419 (Pip5k1b)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    309419 (Pip5k1b)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.68  1-phosphatidylinositol-4-phosphate 5-kinase
     309419 (Pip5k1b)
Membrane trafficking [BR:rno04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    309419 (Pip5k1b)
 Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    309419 (Pip5k1b)
 Endosome - Golgi transport
  Others
   Others
    309419 (Pip5k1b)
SSDB
Motif
Pfam: PIP5K
Other DBs
NCBI-GeneID: 309419
NCBI-ProteinID: NP_001012761
RGD: 1310914
Ensembl: ENSRNOG00000015232
Vega: OTTRNOG00000000898
UniProt: Q5CZZ9
Position
1:complement(231331836..231610092)
AA seq 539 aa
MSSTAENGDAVPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV
ESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNP
GASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
INIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYF
DTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEEEPLQNAPDAKRPGMQ
KVLYSTAMESIQGPGKSADGIIAENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKK
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKAT
SQEILSSISQEWKDEKQDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTIS
SSSLYVGEHYPHDRTTLYSNSKGLPSSSTFTLEEGTIYLTAEPNALETQDDASVLDVYL
NT seq 1620 nt   +upstreamnt  +downstreamnt
atgtcgtcaactgctgaaaatggagacgccgtacctggaaaacaaaacgaagaaaaaacc
tacaaaaagactgcatcatcagctattaaaggtgccattcagctgggaataggatacaca
gtgggtaatctcacttccaagccagaacgcgatgtcctcatgcaagacttttatgtggtg
gaaagtgtattcctccccagtgaagggagcaatctgaccccagcacatcactacccagac
ttcaggtttaagacatacgccccgctggctttccgctacttccgagaactctttggtatc
aagcccgacgattacttgtactccatctgcagtgaaccgctgatagaactgtccaatcct
ggagccagtggatccttgtttttcttgaccagcgatgatgaatttattatcaaaactgtt
cagcataaggaagccgagttcctgcagaagctgctgccaggctattacatgaatctaaac
cagaatccaaggactctcctgccgaaattctatggtctgtattgcatgcagtcaggaggc
atcaacatccgcatcgtggtgatgaacaacgtgctgccgcgtgccatgaggatgcacttg
acctatgacctgaaaggctccacgtacaaacgaagggcgtcccgaaaagagagggagaaa
cccaaccccacgtttaaggacctggacttcctgcaggacatgcatgaggggctgtatttc
gatacagaaacatacaatgcccttatgaagacactacagagagactgccgggtgctggaa
agcttcaagatcatggactacagccttttgctgggtatccacatcttggaccattccctc
aaagacaaagaagaggagcccctccaaaatgcacccgacgcaaagcggccggggatgcag
aaagtcctctactccacagccatggagtccatccagggtccaggcaagtccgcagatggg
atcattgcagagaacccagacacaatgggaggcattccagctaaaagccataagggagaa
aagctgcttctattcatgggcattattgatattctccaatcatataggttaatgaagaag
ttagaacactcctggaaagctcttgtgtatgatggggacaccgtttcagttcatagacca
agtttttatgcagatagatttttaaagtttatgaattccagagttttcaagaaaattcaa
gctctgaaggcctcaccttctaagaaacggtgcaactccatcgctgcactgaaggcaacc
tcccaggagattctgtcctccatcagccaagaatggaaggatgagaagcaggatctgtta
accgaagggcagagtttcagcagcctggatgaagaagccctgggatcccgacacaggcct
gacctggtgcccagcacgccgtcattatttgaagctgcttccttagcaaccacaatatca
tcttcttccttatatgtcggtgagcactatccacacgacaggactacgctttactcaaac
agcaaagggttaccttccagttcaaccttcaccttggaagaggggaccatctacctgact
gctgagccaaacgccctggaaacgcaggatgacgcctccgtgctggatgtctatttataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (10)   
   RefSeq(nuc) (8)   
   GenBank (1)   
   EMBL (1)   
Protein domain (1)   
   Pfam (1)   
All databases (49)   

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