KEGG   Rattus norvegicus (rat): 81515Help
Entry
81515             CDS       T01003                                 

Gene name
Lyn, p53Lyn, p56Lyn
Definition
(RefSeq) LYN proto-oncogene, Src family tyrosine kinase
  KO
K05854  
tyrosine-protein kinase Lyn [EC:2.7.10.2]
Organism
rno  Rattus norvegicus (rat)
Pathway
Chemokine signaling pathway
NF-kappa B signaling pathway
Platelet activation
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Long-term depression
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    81515 (Lyn)
 Organismal Systems
  Immune system
   04611 Platelet activation
    81515 (Lyn)
   04662 B cell receptor signaling pathway
    81515 (Lyn)
   04664 Fc epsilon RI signaling pathway
    81515 (Lyn)
   04666 Fc gamma R-mediated phagocytosis
    81515 (Lyn)
   04062 Chemokine signaling pathway
    81515 (Lyn)
  Nervous system
   04730 Long-term depression
    81515 (Lyn)
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    81515 (Lyn)
  Infectious diseases
   05169 Epstein-Barr virus infection
    81515 (Lyn)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     81515 (Lyn)
Protein kinases [BR:rno01001]
 Tyrosine protein kinases
  Src family
   81515 (Lyn)
Membrane trafficking [BR:rno04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    81515 (Lyn)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
RGD: 
Ensembl: 
UniProt: 
Position
5q12
AA seq 512 aa AA seqDB search
MGCIKSKRKDNLNDDGVDMKTQPVRNTDRTIYVRDPTSNKQQRPVPESQLLPGQRFQAKD
PEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAK
VNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVI
KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAW
EIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSAQAFLEEANLMKTLQHD
KLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQIAEGMAYIER
KNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCF
TIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCW
KESAEERPTFDYLQSVLDDFYTATEGQYQQQP
NT seq 1539 nt NT seq  +upstreamnt  +downstreamnt
atgggatgtattaaatcaaaaaggaaagacaatctgaatgacgatggagtagatatgaag
actcaaccagtacgtaatactgaccgaactatttatgtgagagatccaacgtccaataaa
cagcaaaggccagttcctgaatctcaacttttaccaggacagagatttcaagcaaaagat
ccagaggagcaaggggacattgtggtggccttgtatccctatgatggcatccacccagac
gacttgtctttcaagaaaggagaaaagatgaaagttctggaagagcacggggagtggtgg
aaagctaagtccctttcatcaaagagagaaggcttcatccccagcaactacgtggccaag
gtcaacaccttagaaaccgaagagtggttcttcaaggacataacaaggaaagatgcagaa
cgacagcttctggcaccagggaacagtgccggggctttcctgatcagagaaagtgaaact
ttaaagggaagcttctctctttccgtcagagattacgaccctatgcatggcgacgtcatt
aagcactacaaaatcagaagcctggacaatggtggttattacatctctccgaggatcact
tttccctgtatcagtgacatgattaagcattaccaaaagcagtctgatggtctatgcaga
agactggagaaggcatgcatcagtcccaaaccacagaagccatgggataaagatgcttgg
gagatcccccgggagtccattaagctggtgaaaaaactcggcgcagggcagttcggggaa
gtctggatgggttactataacaacagcacaaaagtggctgtaaagaccctcaagcctggc
accatgtctgctcaagcattcctggaagaggccaacctcatgaagaccttgcagcatgac
aagctagtgcggctgtatgccgtggtcaccaaggaggagcccatctacatcattaccgag
ttcatggccaagggtagcttgctggatttcctcaagagtgacgaaggcagcaaggttctg
ctcccgaaactcattgacttttcagctcagattgcagaaggcatggcgtacatcgagcgg
aagaactacatccaccgcgatctgcgagctgccaacgtgctggtctctgagtctctcatg
tgcaagattgcagactttggcctcgcgagagtaatcgaagataatgaatacacagcgagg
gaaggtgccaagttccctatcaagtggacggctccagaggccatcaacttcggctgcttc
actatcaagtctgacgtgtggtccttcggaattctcctgtacgagatcgtcacctatggg
aagattccctacccagggagaactaacgcagatgtgatgaccgcactgtcacaggggtac
cgaatgccacgaatggagaactgtccagatgagctctatgacatcatgaaaatgtgctgg
aaggaatcagcagaggagaggccaacctttgactacttacagagtgtactggatgacttc
tacactgccacggaagggcagtatcagcagcagccatag

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