KEGG   Rattus norvegicus (rat): 316457
Entry
316457            CDS       T01003                                 
Symbol
Pikfyve
Name
(RefSeq) 1-phosphatidylinositol-3-phosphate 5-kinase
  KO
K00921  1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00562  Inositol phosphate metabolism
rno01100  Metabolic pathways
rno04070  Phosphatidylinositol signaling system
rno04145  Phagosome
rno04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    316457 (Pikfyve)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    316457 (Pikfyve)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    316457 (Pikfyve)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    316457 (Pikfyve)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    316457 (Pikfyve)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.150  1-phosphatidylinositol-3-phosphate 5-kinase
     316457 (Pikfyve)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Macropinocytosis
   Kinases
    316457 (Pikfyve)
 Endosome - Golgi transport
  Others
   Others
    316457 (Pikfyve)
SSDB
Motif
Pfam: PIP5K Cpn60_TCP1 DEP FYVE YiiM_3-alpha
Other DBs
NCBI-GeneID: 316457
NCBI-ProteinID: NP_001414206
RGD: 1592067
Ensembl: ENSRNOG00000015158
Position
9:74057488..74151610
AA seq 2097 aa
MATDDKSSPTLDSANDLPHSPASPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERG
EGGQGEQQSPSSSWSSPQIPSRTQSVRSPVPYKKQLNEELHRRSSVLDSRRKAEPACGGH
DPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHC
RLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDST
CSVSILDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSSSALSTRLVSVQEDAGKSP
ARNRSASITNLSLDRSGSPMVPSYETSVSPQANRNYIRTETTEDERKILLDSAQLKDLWK
KICHHTSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLD
CVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQI
AEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPH
PADQKEYLVSDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENE
EKQAMERLLSANHNHMMALLQQLLQNESLSSSWRDIIVSLVCQVVQTVRPDVKHQDDDMD
IRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMNSCIKNPKILLLKCSIEYLYREETK
FTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVL
ERISRMTQGDLVVSMDQLLTKPHLGTCHKFYMQLFQLPNEQTKTLMFFEGCAQHLGCTIK
LRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLTQSPSFHFLAEGRGEEG
ASQEQVSGSSLPQDPECPFDALSSDDSTLLESRTVPEKGELDNKSVPQAVASLKHQDYTT
PTCPAGIPCALFALVPESLLPLHMDQQDAVGDEQPETSQQTVEQQDPKSQMRAFRDPLQD
DTGMYVTEEVTSSEDKRKTYSLTFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYF
PEQIYWSPLLNKEVKEMESRRKKQLLRDLSGLQSMNGNVQTKSIQVLPSHELVSTRIAEH
LGDSQSLGRMLADYRARGGRIQSKHLDPFVHSKDTSCTSGSKSGNKTESDEERGLIPSDV
LWPTKVDCLNPANHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERY
CFRSSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICKQ
VTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASFS
YSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYLAVDERLASLKTDTFSK
TREEKMEDIFAQKEMEEGEFKSWTEKMQARLMSSCVDTPQQLQSVLESLIAKKQSLCEAL
QAWNSRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDTSPRNISPGLHNGEKEDRF
LTTLSSQSSTSSTHLQLPTPPEALAEQLVGGPSDLDTASGSEDVFDGHLLGSTDSQVKEK
STMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYR
NALEELSKATLWNNAEEGLPTNSALDNRPKSSSPIRLPEVSGGQTNRTVEGEPQPTKKAS
GMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGMESQGLEPQDEVDGGDTQK
KQLTNPHVELQFSDANAKFYCRLYYAGEFHKMREVILGSSEEDFIRSLSHSSPWQARGGK
SGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGY
KNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLK
MVRDNPLYIRSHSKSVLRTSIHSDAHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTF
TWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLDLNC
NT seq 6294 nt   +upstreamnt  +downstreamnt
atggccacagatgacaagagctccccgacattggactctgctaatgacttgcctcactct
cctgccagtccctctcacctcactcactttaaaccgttgactcctgaccaggatgagccc
cccttcaagtcagcatatagttcgtttgtaaatctttttcgttttaacaaagagagagga
gaagggggccaaggagagcagcagtctccgagttcaagttggtccagccctcagatccct
tcaaggacacagtctgtgaggtcgcctgtaccttataaaaagcagcttaatgaggagctt
caccggcgctcttcagtgttagactccagaaggaaagcagaaccagcctgtggaggtcat
gacccacgtacagctgtccagcttcgaagcctcagcacagtgttgaaacgcctcaaggaa
atcatggaaggaaaaagccaggacagtgacctgaagcagtattggatgccagatagccag
tgtaaagagtgctatgactgcagtgaaaagtttaccacctttaggcgcagacaccattgc
agactgtgtgggcagattttctgcagtcgttgttgtaatcaagaaatccctggaaaattt
atgggctatacaggagacctccgggcatgcacatactgtagaaaaatagccttaagttac
gctcattccacagacagtaattccattggggaggacttgaatgctctttcagattcaact
tgctctgtgtctatacttgatccaagtgaacctcggacccctgttgggagtaggaaagcc
agtcgtaacatcttcttagaggatgacttagcctggcaaagtttgattcatccggactcc
tcgagtagtgctctttcaacaagacttgtatctgttcaagaggatgctgggaagtctcct
gctcgaaacagatcagccagcattactaatctgtcactggatcggtctggttctcctatg
gttccttcatatgagacatctgtgagtccccaggctaaccgaaactacatcaggacagag
actactgaggatgaacgcaaaattcttctggacagtgctcagttaaaggatctgtggaag
aaaatctgccatcataccagtgggatggaatttcaggatcaccgttactggttgagaaca
catcccaactgcattgtaggaaaggaattagtcaactggctaatcagaaatggacacatt
gctacaagggcacaagctatagcaattggacaagcaatggtcgatggacgttggttggat
tgtgtcagtcatcatgaccagcttttcagggacgagtatgcattgtatagaccactgcag
agtactgaattttctgagacaccttctccagacagtgactcggtgaactctgtggaagga
cactctgagccatcctggtttaaagacataaaatttgatgacagtgacacagaacagatt
gctgaagaaggtgacgataatttggctaattctgccagtcctagcaagcgcacctcagtc
agcagtttccagtccacagtggacagtgactcagccgcttctatcagcctgaacgtggag
ctggacaacgtgaacttccatatcaagaagccctccaagtacccacatgtgccccctcac
cctgctgaccaaaaagagtatttggtttctgacactggaggacagcagctctcaataagt
gatgccttcatcaaagagtccttatttaatcgacgggtagaagaaaaatccaaagagctg
ccttttacccctttgggctggcatcataacaacctggaactcttgcgggaggagaatgag
gagaagcaagccatggaaaggctgctttcagctaatcataaccacatgatggccttactc
cagcagctgcttcaaaatgagtcattgtcatcatcttggagggacatcattgtgtcacta
gtttgtcaggttgttcagacagtccgacctgacgtcaagcaccaggatgatgacatggat
atccgtcagtttgtccatatcaagaagatcccaggtggaaagaaatttgattccgtggtt
gtcaatggctttgtttgtaccaaaaacattgcacataaaaagatgaattcctgtattaaa
aaccccaaaatccttctgttgaagtgttctattgagtatctctatagagaagaaactaag
tttacttgcattgaccccattgtgcttcaggaaagggaattcttgaagaattatgttcaa
cgaatagttgatgttcgacccacattggttctcgttgagaaaacagtgtctcggattgct
caagacatgttactggaacatggcattactctggtcattaatgtaaagtcacaagtttta
gaaagaatcagtcgaatgacccaaggagatttagtggtgtccatggaccagctgctcacc
aaaccccacctgggcacttgccacaagttttatatgcagctctttcagttgcctaacgaa
caaaccaaaacactgatgttttttgaaggctgtgcacagcacctcggctgcacaatcaag
ctcagaggaggctctgattatgagctggctcgagttaaggagatcctaatatttatgatc
tgtgtagcttatcattctcagctagaaatctcctttctcatggatgagtttgctatgcct
ccaacgttaacacaaagcccttcgttccattttctggctgagggaagaggggaagaggga
gcttctcaggagcaggtcagtggcagctcccttccccaggatcctgagtgcccctttgat
gccctgtcttctgatgatagcactttgttggaatcaaggactgtgcctgagaagggtgag
ctggacaataaaagtgtcccacaggctgttgcctccttgaagcatcaagattacaccacc
cccacttgcccagcaggtatcccctgtgctctctttgcactggtacccgagtcattgttg
cctctccatatggatcaacaggatgctgtaggagatgaacagccagagacatcacagcaa
acggttgagcaacaggaccccaaaagccagatgagagcttttagagaccctctacaggat
gacactggaatgtatgttactgaggaagtcacctcctctgaagataaacgaaagacttac
tccttgacatttaaacaggaattaaaagacgtcatcctctgtatctctccagttattaca
ttccgtgaacctttccttttaactgaaaaggggatgaggtgctcaactcgagattacttt
ccagagcagatttactggtctcctcttctcaataaagaggtgaaggaaatggagagcagg
aggaagaaacagctgctcagggatctctctggacttcagagcatgaatggcaatgttcag
accaagtccatacaagtcttaccttcacatgagctagtgagcaccaggatcgctgaacat
ctgggggacagccagagcttgggtagaatgctagctgactatcgagctagaggaggaaga
attcagtcaaaacatttggacccttttgtccattcaaaagatacatcatgtacttcaggg
agcaaatcaggaaacaaaactgagagtgatgaagagaggggattgattccaagtgatgtc
ttatggccaacaaaggtggactgtctgaatcctgctaaccaccagaggctctgcgtgctc
ttcagcagttcttctgcccagtccagcaatgcgcccagtgcttgtgtcagcccttggatt
gtaacaatggagttttatggaaagaatgaccttacactgggaatatttttagaaagatac
tgtttcaggtcttcttaccagtgtcctagcatgttctgtgatacccccatggttcatcac
attcgacgctttgttcatggccaaggctgtgtacagataatcctgaaggagttggattct
ccagtgcctggatatcaacatacaattctcacatattcctggtgcagaatctgcaaacaa
gtaacaccagttgttgctctttcaaatgaatcctggtcgatgtcatttgcaaaatacctt
gaacttcgattttatggccaccagtacactcgcagagccaatgctgagccctgcggtcac
tccatccaccatgattatcaccagtatttctcttataatcagatggtggcatctttcagt
tactctcctattcggcttcttgaagtgtgtgttccactgccaaaaatattcattaagcgc
caagccccgctgaaggtgtctcttcttcaggacctcaaggacttctttcagaaggtttca
caggtgtacctagctgttgatgaaagacttgcgtccttgaaaacagatacatttagcaaa
accagagaggaaaagatggaggatatctttgcacaaaaggagatggaggagggtgagttt
aagagctggactgagaagatgcaggcgcggctcatgtcctcgtgtgtggacaccccgcag
caactgcagtccgttctcgagtcactcattgccaagaagcaaagcctctgtgaggcgctc
caagcgtggaacagcaggttacaggacctcttccagcaggaaaaaggtaggaagaggcct
tcggttcctcccagtcctggaagactgagacaaggagaagagagcaagataagtgcaatg
gacacatctccaaggaatatttctccaggacttcacaacggagaaaaagaggatcgcttc
ttgacaaccctgtccagtcagagctccacgagctccacccatctccagctgcccactcct
cctgaggccctggctgagcagttagtgggagggccttctgacctggacacagccagtggc
tctgaagatgtatttgatgggcatttgctgggatccacagacagccaggtgaaggaaaag
tcaaccatgaaagccatctttgctaatttgcttccaggaaacagctataatcccattcca
tttcctttcgatccagataaacattatttaatgtatgaacacgaacgggtgcccattgct
gtctgtgagaaagagcccagctccatcattgcttttgcactcagttgtaaagaataccga
aatgccttagaggaattgtccaaagcaactctgtggaacaatgctgaagaagggcttcca
accaatagtgctttagataacagaccaaaaagtagcagtcctattagattacctgaagtc
agtggaggacagacaaaccgtacagtagaaggagaacctcaaccaaccaaaaaagcttca
ggaatgctgtccttcttcagaggaacagcagggaagagccctgatctgtcttctcagaag
agagagaccttacgtggggccgacagtgcatactaccaggttgggcagactggcaaggag
gggatggagagtcaaggccttgagcctcaagatgaagtagatggaggagacacacagaag
aaacaactcacaaatccccatgtggaacttcaattttctgacgctaacgccaagttttac
tgtcgactgtactacgcgggagagttccataagatgcgggaagtgattctgggcagcagt
gaggaagatttcattcgttccctttctcactcatcaccctggcaggcccggggaggcaag
tcaggagctgctttctatgccacagaagatgatagatttattttgaagcaaatgcctcgt
ctggaagtccagtctttccttgactttgcaccgcactacttcaattatatcaccaatgct
gttcaacagaagaggcccactgctttggctaaaattcttggtgtgtacagaattggttac
aagaactctcagaacaacactgagaagaagttagatctccttgtcatggaaaatcttttc
tatgggagaaagatggcacaggtttttgatttgaagggttcacttaggaatcgaaatgtg
aaaactgacactgggaaagagagctgtgacgtggttctgctggatgagaacctcctgaag
atggttcgagacaaccctctgtatattcgttcccattccaaatctgtgctgagaacctcc
atccatagcgacgcccatttcctttccagccacctcattatagactattctttgctggtt
ggtcgagatgacactagcaatgagctggttgttgggatcatagattacattcgaacattt
acatgggacaaaaaactcgagatggttgtgaagtcaacaggaattttaggaggacaaggt
aaaatgccaaccgtggtctctccagagttatacaggactagattttgtgaagcaatggac
aagtatttcttgatggtgccagaccactggacagggttggatctcaattgctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (19)   
   UniProt (1)   
   RefSeq(pep) (18)   
DNA sequence (20)   
   RefSeq(nuc) (18)   
   GenBank (1)   
   EMBL (1)   
Protein domain (5)   
   Pfam (5)   
All databases (68)   

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