KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104659593
Entry
104659593         CDS       T03989                                 
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR
  KO
K12406  pyruvate kinase isozymes R/L [EC:2.7.1.40]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00010  Glycolysis / Gluconeogenesis
rro00620  Pyruvate metabolism
rro01100  Metabolic pathways
rro01200  Carbon metabolism
rro01230  Biosynthesis of amino acids
rro04910  Insulin signaling pathway
rro04930  Type II diabetes mellitus
rro04932  Non-alcoholic fatty liver disease
rro04950  Maturity onset diabetes of the young
Module
rro_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
rro_M00002  Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:rro00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    104659593 (PKLR)
   00620 Pyruvate metabolism
    104659593 (PKLR)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    104659593 (PKLR)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    104659593 (PKLR)
   04950 Maturity onset diabetes of the young
    104659593 (PKLR)
   04932 Non-alcoholic fatty liver disease
    104659593 (PKLR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rro04147]
    104659593 (PKLR)
Enzymes [BR:rro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     104659593 (PKLR)
Exosome [BR:rro04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   104659593 (PKLR)
SSDB
Motif
Pfam: PK PK_C IMPDH HpcH_HpaI
Other DBs
NCBI-GeneID: 104659593
NCBI-ProteinID: XP_010357969
UniProt: A0A2K6QEV0
Position
8:41874593..41886471
AA seq 574 aa
MSIQENIPSLQRWSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ
LPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS
HGSHEYHAESIANVREAVESFAASPLGYRPVAIALDTKGPEIRTGILQGGPESEVELVKG
SQVLVTVDPAFRTRGNANTVWVDYPNVVGVVPVGGRIYIDDGLISLVVQKIGPEGLVTQV
ENGGVLGSHKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAA
LGPEGQGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC
NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKM
QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRS
AQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESG
KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS
NT seq 1725 nt   +upstreamnt  +downstreamnt
atgtcgatccaggagaacataccatccctgcagcgctggtcatgggtctctaagtcccaa
agagacttagccaagtccatcctgattggagctccaggagggccagcggggtatcttcgg
cgggctagtgtggcccaactgacccaggagctgggcactgccttcttccagcagcagcag
ctgccagctgctatggcagacaccttcctggaacacctctgcctactggacattgactcc
gagcccgtggctgctcgcagtaccagcatcatcgccaccatcgggccggcatctcgctcc
gtggagcgcctcaaggagatgatcaaggccgggatgaacattgcgcgactcaatttctcc
cacggctcccacgagtaccacgctgagtccatcgccaacgtccgggaggcggtggagagc
tttgcagcttccccgctcggctaccggcccgtggccatcgccctggacaccaagggaccg
gagatccgcactgggatcctgcaggggggtccggagtcggaagtggagctggtgaagggc
tcccaggtgctggtgactgtggaccccgcgtttcggacgcgggggaacgcgaacaccgtg
tgggtggactaccccaatgttgtcggggtcgtgccggtggggggccgcatctacattgac
gacgggctcatctccctagtggtccagaaaatcggcccagagggactggtgacccaagtg
gagaacggtggtgtcctgggcagccataaaggcgtgaacttgccgggggcccaggtggac
ttgcccgggctgtccgagcaggacgtccgggacctgcgcttcggggtggagcatggagtg
gacatcgtgtttgcctcctttgtgcggaaagccagcgacgtggctgctgtcagggctgct
ctggggccagaaggacagggcatcaagatcatcagcaaaattgagaaccacgaaggcgtg
aagaggtttgatgaaatcctggaggtgagcgatggcatcatggtggcacggggggaccta
ggcatcgagattccagcagagaaggtttttctggctcagaagatgatgattgggcgctgc
aacttggcgggcaagcctgttgtctgtgccacacagatgctggagagcatgattaccaag
ccccggccaacgagggcagagacaagtgatgtggccaatgctgtgctagatggggccgac
tgcatcatgctgtcaggggagactgccaaaggcaacttccctgtggaagccgtgaagatg
cagcatgcgattgcccgggaggcagaggctgcagtgtaccaccggcagctgtttgaggag
ctacgtcgggcagcaccactgagccgtgatcccactgaggtcaccgccattggcgccgtg
gaggctgccttcaagtgctgtgctgctgccatcatcgtactgaccacaactggccgctca
gcccagcttctgtctcggtaccgacctcgggcagcagtcattgctgtcacccgctctgcc
caagctgcccgccaggtccacttatgccgaggcgtcttccccttgctttaccgtgaacct
ccagaagccatctgggcagatgacgtagatcgccgggtgcaatttggcattgaaagtgga
aagctccgtggcttcctccgtgttggagacctggtgattgtggtgacaggctggcgacct
ggctccggctacaccaacatcatgcgggtgctgagcatatcctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (9)   
   KEGG MODULE (2)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (44)   

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