KEGG   Sorex araneus (European shrew): 101538553
Entry
101538553         CDS       T07854                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
sara  Sorex araneus (European shrew)
Pathway
sara01522  Endocrine resistance
sara04010  MAPK signaling pathway
sara04012  ErbB signaling pathway
sara04014  Ras signaling pathway
sara04024  cAMP signaling pathway
sara04068  FoxO signaling pathway
sara04071  Sphingolipid signaling pathway
sara04137  Mitophagy - animal
sara04140  Autophagy - animal
sara04141  Protein processing in endoplasmic reticulum
sara04210  Apoptosis
sara04215  Apoptosis - multiple species
sara04217  Necroptosis
sara04310  Wnt signaling pathway
sara04380  Osteoclast differentiation
sara04510  Focal adhesion
sara04530  Tight junction
sara04620  Toll-like receptor signaling pathway
sara04621  NOD-like receptor signaling pathway
sara04622  RIG-I-like receptor signaling pathway
sara04625  C-type lectin receptor signaling pathway
sara04657  IL-17 signaling pathway
sara04658  Th1 and Th2 cell differentiation
sara04659  Th17 cell differentiation
sara04660  T cell receptor signaling pathway
sara04664  Fc epsilon RI signaling pathway
sara04668  TNF signaling pathway
sara04722  Neurotrophin signaling pathway
sara04723  Retrograde endocannabinoid signaling
sara04728  Dopaminergic synapse
sara04750  Inflammatory mediator regulation of TRP channels
sara04910  Insulin signaling pathway
sara04912  GnRH signaling pathway
sara04914  Progesterone-mediated oocyte maturation
sara04917  Prolactin signaling pathway
sara04920  Adipocytokine signaling pathway
sara04926  Relaxin signaling pathway
sara04930  Type II diabetes mellitus
sara04931  Insulin resistance
sara04932  Non-alcoholic fatty liver disease
sara04933  AGE-RAGE signaling pathway in diabetic complications
sara04935  Growth hormone synthesis, secretion and action
sara04936  Alcoholic liver disease
sara05010  Alzheimer disease
sara05012  Parkinson disease
sara05016  Huntington disease
sara05017  Spinocerebellar ataxia
sara05020  Prion disease
sara05022  Pathways of neurodegeneration - multiple diseases
sara05132  Salmonella infection
sara05133  Pertussis
sara05135  Yersinia infection
sara05142  Chagas disease
sara05145  Toxoplasmosis
sara05152  Tuberculosis
sara05161  Hepatitis B
sara05162  Measles
sara05166  Human T-cell leukemia virus 1 infection
sara05167  Kaposi sarcoma-associated herpesvirus infection
sara05169  Epstein-Barr virus infection
sara05170  Human immunodeficiency virus 1 infection
sara05171  Coronavirus disease - COVID-19
sara05200  Pathways in cancer
sara05208  Chemical carcinogenesis - reactive oxygen species
sara05210  Colorectal cancer
sara05212  Pancreatic cancer
sara05231  Choline metabolism in cancer
sara05415  Diabetic cardiomyopathy
sara05417  Lipid and atherosclerosis
sara05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sara00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101538553 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101538553 (MAPK10)
   04012 ErbB signaling pathway
    101538553 (MAPK10)
   04014 Ras signaling pathway
    101538553 (MAPK10)
   04310 Wnt signaling pathway
    101538553 (MAPK10)
   04668 TNF signaling pathway
    101538553 (MAPK10)
   04068 FoxO signaling pathway
    101538553 (MAPK10)
   04071 Sphingolipid signaling pathway
    101538553 (MAPK10)
   04024 cAMP signaling pathway
    101538553 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101538553 (MAPK10)
   04137 Mitophagy - animal
    101538553 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    101538553 (MAPK10)
   04215 Apoptosis - multiple species
    101538553 (MAPK10)
   04217 Necroptosis
    101538553 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101538553 (MAPK10)
   04530 Tight junction
    101538553 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101538553 (MAPK10)
   04621 NOD-like receptor signaling pathway
    101538553 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    101538553 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    101538553 (MAPK10)
   04660 T cell receptor signaling pathway
    101538553 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    101538553 (MAPK10)
   04659 Th17 cell differentiation
    101538553 (MAPK10)
   04657 IL-17 signaling pathway
    101538553 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    101538553 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101538553 (MAPK10)
   04920 Adipocytokine signaling pathway
    101538553 (MAPK10)
   04912 GnRH signaling pathway
    101538553 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    101538553 (MAPK10)
   04917 Prolactin signaling pathway
    101538553 (MAPK10)
   04926 Relaxin signaling pathway
    101538553 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    101538553 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    101538553 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    101538553 (MAPK10)
   04722 Neurotrophin signaling pathway
    101538553 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101538553 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101538553 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101538553 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    101538553 (MAPK10)
   05231 Choline metabolism in cancer
    101538553 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101538553 (MAPK10)
   05212 Pancreatic cancer
    101538553 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101538553 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    101538553 (MAPK10)
   05161 Hepatitis B
    101538553 (MAPK10)
   05171 Coronavirus disease - COVID-19
    101538553 (MAPK10)
   05162 Measles
    101538553 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101538553 (MAPK10)
   05169 Epstein-Barr virus infection
    101538553 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101538553 (MAPK10)
   05135 Yersinia infection
    101538553 (MAPK10)
   05133 Pertussis
    101538553 (MAPK10)
   05152 Tuberculosis
    101538553 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101538553 (MAPK10)
   05142 Chagas disease
    101538553 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101538553 (MAPK10)
   05012 Parkinson disease
    101538553 (MAPK10)
   05016 Huntington disease
    101538553 (MAPK10)
   05017 Spinocerebellar ataxia
    101538553 (MAPK10)
   05020 Prion disease
    101538553 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    101538553 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101538553 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    101538553 (MAPK10)
   05415 Diabetic cardiomyopathy
    101538553 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101538553 (MAPK10)
   04936 Alcoholic liver disease
    101538553 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    101538553 (MAPK10)
   04931 Insulin resistance
    101538553 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101538553 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101538553 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sara01001]
    101538553 (MAPK10)
Enzymes [BR:sara01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101538553 (MAPK10)
Protein kinases [BR:sara01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101538553 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 101538553
NCBI-ProteinID: XP_004614399
Position
Unknown
AA seq 464 aa
MSLHLLYYCSEPILDVKLAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSANDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccacttattgtactactgcagtgaaccaatcttggatgtgaaacttgccttt
tgtcagggatttgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagtcgacaaccaattctacagtgtggaagtgggtgactcaaccttcactgtt
ctcaagcgctaccagaatttgaagccgattggctctggggctcagggaatagtttgtgct
gcgtatgatgccgtccttgacagaaatgtggctattaagaagctcagcagacccttccag
aaccaaacgcacgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccaa
gatgtttatttagtaatggaattgatggatgccaacttgtgtcaggtgattcaaatggaa
ttagaccacgagcgaatgtcctacctgctgtaccaaatgttgtgtggcatcaagcacctt
cactctgctggtattattcacagggatttgaagccgagtaatattgtagtcaagtctgac
tgtacactgaaaattctcgactttggactggcccggaccgcaggcacaagcttcatgatg
accccttacgtggtgacacgttactacagagccccggaggttatcctgggaatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccgggaagggactatattgatcagtggaacaaggtaattgagcaactagga
acaccatgtccggaattcatgaagaaattgcaaccgacagtcagaaactatgtggagaat
cgtcccaagtacgcaggactcacctttcccaagctcttccctgactccctctttcccgca
gactccgagcacaataaactcaaagccagtcaagccagggatttgttgtcgaagatgcta
gtgattgatccagccaaaagaatatcagtggatgatgcgttgcagcacccgtatatcaac
gtctggtacgaccccgctgaagtggaggcgcctccgcctcagatatatgacaaacagctg
gatgaaagagaacacaccattgaagaatggaaagaacttatctacaaggaagtaatgaat
tcagaagaaaagactaaaaatggtgtagtaaaaggacaaccttctccttcaggtgcagcc
gtgaacagcagcgagagtctccctccgtcctcgtcagccaacgacatctcctccatgtcc
actgaccagaccctggcctcggacactgacagcagcctggaagcctcagcgggacccctg
ggttgttgcaggtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (70)   
   KEGG PATHWAY (70)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (8)   
   Pfam (8)   
All databases (100)   

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