KEGG   Staphylococcus aureus 08BA02176 (LA-MRSA): C248_2063
Entry
C248_2063         CDS       T02339                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
saub  Staphylococcus aureus 08BA02176 (LA-MRSA)
Pathway
saub00290  Valine, leucine and isoleucine biosynthesis
saub00620  Pyruvate metabolism
saub01100  Metabolic pathways
saub01110  Biosynthesis of secondary metabolites
saub01210  2-Oxocarboxylic acid metabolism
saub01230  Biosynthesis of amino acids
Module
saub_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:saub00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    C248_2063 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    C248_2063 (leuA)
Enzymes [BR:saub01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     C248_2063 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AFR74017
Position
2080948..2082477
AA seq 509 aa
MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIEAGFPASSTGSFKSVQA
IAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIATSPIHLEHKLKMSQEDVLA
SIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVDAGATVINIPDTVGYSYHDEY
AHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAIEGGARRIEGTVNGIGERAGNAA
LEEVALALYVRNDHYGAQTALNLEETKKTSDLISRYAGIRVPRNKAIVGQNAFSHESGIH
QDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGKHAFSEKLKALGYDIDKEAQIDLFKQF
KAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSGLQSAVVVIKDKEGHIYQ
DSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAEVHVNLLIEGKTVNGFGI
DHDILQASCKAYVEAHAKFAAENVEKVGN
NT seq 1530 nt   +upstreamnt  +downstreamnt
atgagtagtcatattcaaatttttgatacgacactaagagacggtgaacaaacaccagga
gtgaattttacttttgatgaacgcttgcgtattgcattgcaattagaaaaatggggtgta
gatgttattgaagctggatttcctgcttcaagtacaggtagctttaaatctgttcaagca
attgcacaaacattaacaacaacggctgtatgtggtttagctagatgtaaaaaatctgac
atcgatgctgtatatgaagcaacaaaagatgcagcgaagccggtcgtgcatgtttttata
gcgacatcacctattcatcttgaacataaacttaaaatgtctcaagaagacgttttagca
tctattaaagaacatgtcacatacgcgaaacaattatttgacgttgttcaattttcacct
gaagatgcaacgcgtactgaattaccattcttagtgaaatgtgtacaaactgccgttgac
gctggagctacagttattaatattcctgatacagtcggctacagttaccatgatgaatat
gcacatattttcaaaaccttaacagaatctgtaacatcttcaaatgaaattatttatagt
gctcattgccatgacgatctaggaatggctgtttcaaatagtttagctgcaattgaaggc
ggtgcgagacgaattgaaggcactgtaaatggtattggtgaacgagcaggtaatgcagca
cttgaagaagtcgcgcttgcactatacgttcgaaatgatcattatggtgctcaaactgcc
cttaatctcgaagaaactaaaaaaacatcggatttaatttcaagatatgcaggtattcga
gtgcctagaaataaagcaattgttggccaaaatgcatttagtcatgaatcaggtattcac
caagatggcgtattaaaacatcgtgaaacatatgaaattatgacacctcaacttgttggt
gtaagcacgactgaacttccattaggaaaattatctggtaaacacgccttctcagagaag
ttaaaagcattaggttatgacattgataaagaagcgcaaatagatttatttaaacaattc
aaggccattgcggacaaaaagaaatctgtttcagatagagatattcatgcgattattcaa
ggttctgagcatgagcatcaagcactttataaattggaaacactgcaactacaatatgtc
tctagcggccttcaaagtgctgttgttgttattaaagataaagagggtcatatttaccag
gattcaagtattggtactggttcaatcgtagcaatttacaatgcagttgatcgtattttc
caaaaagaaacagaattaattgattatcgtattaattctgtcactgaaggtactgatgcc
caagcagaagtacatgtaaatttattgattgaaggtaagactgtcaatggctttggtatt
gatcatgatattttacaagcctcttgtaaagcatacgtagaagcacatgctaaatttgca
gctgaaaatgttgaaaaggtaggtaattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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