KEGG   Saccharomyces cerevisiae (budding yeast): YGR061C
Entry
YGR061C           CDS       T00005                                 
Symbol
ADE6
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
  KO
K01952  phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00230  Purine metabolism
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
Module
sce_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    YGR061C (ADE6)
Enzymes [BR:sce01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.3  phosphoribosylformylglycinamidine synthase
     YGR061C (ADE6)
SSDB
Motif
Pfam: GATase_5 AIRS_C FGAR-AT_N FGAR-AT_linker
Other DBs
NCBI-GeneID: 852952
NCBI-ProteinID: NP_011575
SGD: S000003293
UniProt: P38972
Position
VII:complement(611889..615965)
AA seq 1358 aa
MTDYILPGPKALSQFRVDNLIKDINSYTNSTSVINELRSCYIHYVNGIAQNLSEQDTKLL
EVLLTYDSALDIANDPLARQLNDAVANNLPSSALGEDTYLIRVVPRSGTISPWSSKATNI
AHVCGLQDKVQRIERGLALLIKTVPGFPLLENLNDISLKCVYDRMTQQLYLTEPPNTMSI
FTHEEPKPLVHVPLTPKDTKQSPKDILSKANTELGLALDSGEMEYLIHAFVETMKRDPTD
VELFMFAQVNSEHCRHKIFNADWTIDGIKQQFTLFQMIRNTHKLNPEYTISAYSDNAAVL
DSENDAFFFAPNSTTKEWTSTKERIPLLIKVETHNHPTAVSPFPGAATGSGGEIRDEGAT
GRGSKTKCGLSGFSVSDLLIPGNEQPWELNIGKPYHIASALDIMIEAPLGSAAFNNEFGR
PCINGYFRTLTTKVLNHQGKEEIRGFHKPIMIAGGFGTVRPQFALKNTPITPGSCLIVLG
GQSMLIGLGGGAASSVASGEGSADLDFASVQRGNPEMERRCQQVIDACVALGNNNPIQSI
HDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEIWCNESQERYVLGVSPQDL
SIFEEICKRERAPFAVVGHATAEQKLIVEDPLLKTTPIDLEMPILFGKPPKMSRETITEA
LNLPEANLSEIPSLQDAIQRVLNLPSVGSKSFLITIGDRSVTGLIDRDQFVGPWQVPVAD
VGVTGTSLGETIISTGEAMAMGEKPVNALISASASAKLSVAESLLNIFAADVKSLNHIKL
SANWMSPASHQGEGSKLYEAVQALGLDLCPALGVAIPVGKDSMSMKMKWDDKEVTAPLSL
NITAFAPVFNTSKTWTPLLNRNTDDSVLVLVDLSAKQETKSLGASALLQVYNQVGNKSPT
VYDNAILKGFLESLIQLHQQKEDIVLAYHDRSDGGLLITLLEMAFASRCGLEINIDGGDL
ESQLTNLFNEELGAVFQISAKNLSKFEKILNENGVAKEYISIVGKPSFQSQEIKIINSTT
NDVIYANSRSELEQTWSKTSYEMQKLRDNPKTAEEEFASITDDRDPGLQYALTYNPADDM
KIGLELSSQRPKVAILREQGVNGQMEMAWCFQQAGFNSVDVTMTDLLEGRFHLDDFIGLA
ACGGFSYGDVLGAGAGWAKSVLYHEGVRSQFSKFFNERQDTFAFGACNGCQFLSRLKDII
PGCENWPSFERNVSEQYEARVCMVQISQEKDNSSEESVFLNGMAGSKLPIAVAHGEGKAT
FSKSAEQLEKFEKDGLCCIRYVDNYGNVTERFPFNPNGSTNGIAGIKSPNGRVLAMMPHP
ERVCRLEANSWYPEGKYEEWGGYGPWIRLFRSARRWVG
NT seq 4077 nt   +upstreamnt  +downstreamnt
atgactgattatattttgccgggtcccaaggccttatctcagttcagagtcgataatcta
attaaagatataaactcctatacaaacagtacttctgtcatcaatgaattgcgttcgtgt
tacattcactatgtcaacggcatcgctcaaaatttgtctgaacaggacactaaattgcta
gaagttttgttgacttacgattctgctttagatattgctaacgatccattagcaagacaa
ttaaacgatgctgtcgctaataatttacccagttcagctcttggcgaagacacatatttg
attagagttgttcctagatcaggcactatctctccttggtcttccaaggctactaatatt
gctcatgtatgcgggctacaagacaaagttcaacgtattgaaagaggtttagccttactc
ataaagactgttccaggtttccctcttttggaaaatctaaatgatatttcattgaagtgt
gtctacgataggatgacacaacaattatatctgaccgaaccaccaaatacgatgagtatt
ttcacacatgaagagccaaagccattagttcacgttcctttaactcctaaggacactaaa
cagtctccaaaggatattttatccaaagctaatacggaattgggtttagctctagatagt
ggagaaatggaatatttgattcatgcattcgtcgaaactatgaaaagagatcctactgat
gttgagttatttatgttcgctcaagttaattctgaacattgtcgtcacaagatcttcaat
gctgattggaccattgatggaataaaacaacaattcaccttgtttcaaatgattagaaat
acccataaattaaacccagaatatactattagcgcctattctgataatgcagccgttttg
gatagtgaaaatgatgcctttttctttgcaccaaattcaactacaaaggaatggacctct
acaaaggaaagaattccattacttatcaaagtcgaaactcacaaccatccaacagccgtg
tctcctttcccaggtgctgctacaggttctggtggtgaaatcagagacgagggtgctaca
ggcagaggttccaagactaagtgtggtttgagtggattctctgtcagcgaccttttgata
ccaggtaatgaacaaccttgggagttgaatattggtaagccttaccatattgcatctgca
ttagatattatgattgaggctcctttgggttcagctgcatttaacaatgagtttggtaga
ccttgtataaacggttacttcagaactttaactacaaaggttttgaatcaccaagggaag
gaggaaatcagagggttccacaagccaattatgattgcgggtggtttcggtactgttaga
cctcaatttgctttgaagaacaccccaataactccaggctcttgtttaattgtacttggt
ggtcaatctatgctgattggtttaggtggtggtgctgcttcttctgtagcttccggtgaa
ggttccgccgatttggattttgcttctgtacaaagagggaaccccgaaatggaacgtcgt
tgccaacaagtgattgacgcttgtgttgccttaggtaacaataatcctatccaatctatt
cacgatgttggtgctggtgggttatccaacgctttgccagaattggttcatgacaatgac
ttgggtgctaaattcgatattagaaaggtcctctccttagaacctggtatgtcaccaatg
gaaatttggtgtaatgaatcacaagaacgttatgttcttggtgtttctcctcaagactta
tccattttcgaggaaatctgtaagagagaaagagcaccatttgctgtcgtcggtcacgca
accgctgaacaaaaattgattgtagaagatcctcttttgaaaacaactccaattgattta
gaaatgccaattttatttggtaagcctccaaagatgtcaagagaaaccataactgaagca
ctaaatctaccagaggcaaatttgagcgaaattccttccctacaagatgctattcaaaga
gttctaaacttaccatctgttggctcaaagtcatttttgattactattggtgacagatcc
gtcacaggtctaattgatagggatcaatttgttggtccttggcaagtacctgttgcggat
gtcggtgttaccggtacctctttgggtgagacaataatttccacaggtgaagccatggct
atgggtgaaaaaccagttaacgccctaatctccgcatctgcttccgctaaattatctgtg
gcagaatctttattgaacatattcgctgctgatgtgaaatctttaaatcatatcaagcta
tctgctaactggatgtctccagcctctcatcaaggtgagggttctaagttatatgaagcc
gttcaagcattaggtctggatttatgtcctgcattaggtgttgctatccctgttggtaag
gattccatgtccatgaagatgaaatgggatgataaggaagttactgcaccattgtcattg
aatatcacagcatttgcaccagttttcaacactagtaaaacgtggactccattgctaaat
agaaacacagatgattctgtccttgtcttggttgatctatcagctaaacaagagactaag
tcactaggtgcctctgctttgttgcaagtttacaaccaagttggtaacaagtcgcctact
gtgtatgataacgccattttgaagggtttcttggaaagtttaatccaattgcatcaacaa
aaggaggatatagtgcttgcctaccatgataggtctgatggtggtctactaatcacttta
ctggaaatggcatttgcttccagatgcggcttagaaatcaacattgacggtggagaccta
gaaagtcaattaacaaacctattcaatgaagaattaggtgcagtattccagatttctgct
aagaacttgagcaagttcgaaaaaatcttgaacgagaacggagttgctaaagaatatatt
tctattgttggtaagccatccttccaaagccaggaaatcaagattattaactccacaaca
aatgatgtaatttacgccaattcgagatctgaattggagcaaacttggagtaagacatct
tacgaaatgcagaaattgagagacaatccaaaaacagccgaagaagagtttgccagtatc
acggacgatagagatcccggtttgcagtatgccctaacatacaacccagccgatgatatg
aagatcggattagaattatccagtcaaaggccaaaggttgctatcttaagagagcaaggt
gtgaacggtcaaatggaaatggcatggtgcttccaacaagctggattcaactcagtggat
gtcactatgacagatttgctagaaggtaggttccatttggatgacttcatcggtcttgcc
gcatgtggtggtttctcttatggtgatgtcttaggtgcaggtgcgggttgggctaaatcc
gtattgtatcacgaaggtgtgcgctcgcaattttctaagttcttcaatgaaagacaagat
acatttgcttttggtgcttgtaatggttgtcaattcttgagtagattaaaagatatcata
cccgggtgtgaaaactggccaagtttcgaaagaaatgttagtgaacaatatgaagcccgt
gtatgtatggtgcaaatatctcaagaaaaggacaattctagcgaggaatctgttttcttg
aatggcatggcaggatccaaattgccaattgctgtcgcacatggtgaaggtaaagcaaca
ttttctaaaagcgctgaacaactggaaaagttcgaaaaggatggtttatgttgtataagg
tatgtggacaactacggtaacgtcaccgaaaggttccccttcaaccccaatgggtcgacc
aatggtattgccggtatcaagtcaccaaatggtagagtgcttgccatgatgccacatcct
gaaagagtttgcagattggaggccaattcctggtatccagagggcaaatacgaagagtgg
ggtggatacggtccatggattagattattcagatctgccagaagatgggtcggttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (47)   

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