KEGG   Saccharomyces cerevisiae (budding yeast): YHR007C
Entry
YHR007C           CDS       T00005                                 
Symbol
ERG11, CYP51
Name
(RefSeq) sterol 14-demethylase
  KO
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00100  Steroid biosynthesis
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
Module
sce_M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    YHR007C (ERG11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:sce00199]
    YHR007C (ERG11)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.154  sterol 14alpha-demethylase
     YHR007C (ERG11)
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.36  sterol 14alpha-demethylase (ferredoxin)
     YHR007C (ERG11)
Cytochrome P450 [BR:sce00199]
 Cytochrome P450, animal type
  CYP51 family
   YHR007C (ERG11)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 856398
NCBI-ProteinID: NP_011871
SGD: S000001049
UniProt: P10614
Structure
Position
VIII:complement(120091..121683)
AA seq 530 aa
MSATKSIVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPLVF
YWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADV
SAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRD
SKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPIN
FVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVKMT
DQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLL
QEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYF
PNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQL
GVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKRNPEQKI
NT seq 1593 nt   +upstreamnt  +downstreamnt
atgtctgctaccaagtcaatcgttggagaggcattggaatacgtaaacattggtttaagt
catttcttggctttaccattggcccaaagaatctctttgatcataataattcctttcatt
tacaatattgtatggcaattactatattctttgagaaaggaccgtccacctctagtgttt
tactggattccatgggtcggtagtgctgttgtgtacggtatgaagccatacgagtttttc
gaagaatgtcaaaagaaatacggtgatattttttcattcgttttgttaggaagagtcatg
actgtgtatttaggaccaaagggtcacgaatttgtcttcaacgctaagttggcagatgtt
tcagcagaagctgcttacgctcatttgactactccagttttcggtaaaggtgttatttac
gattgtccaaattctagattgatggagcaaaagaagtttgttaagggtgctctaaccaaa
gaagccttcaagagctacgttccattgattgctgaagaagtgtacaagtacttcagagac
tccaaaaacttccgtttgaatgaaagaactactggtactattgacgtgatggttactcaa
cctgaaatgactattttcaccgcttcaagatcattattgggtaaggaaatgagagcaaaa
ttggataccgattttgcttacttgtacagtgatttggataagggtttcactccaatcaac
ttcgtcttccctaacttaccattggaacactatagaaagagagatcacgctcaaaaggct
atctccggtacttacatgtctttgattaaggaaagaagaaagaacaacgacattcaagac
agagatttgatcgattccttgatgaagaactctacctacaaggatggtgtgaagatgact
gatcaagaaatcgctaacttgttaattggtgtcttaatgggtggtcaacatacttctgct
gccacttctgcttggattttgttgcacttggctgaaagaccagatgtccaacaagaattg
tacgaagaacaaatgcgtgttttggatggtggtaagaaggaattgacctacgatttatta
caagaaatgccattgttgaaccaaactattaaggaaactctaagaatgcaccatccattg
cactctttgttccgtaaggttatgaaagatatgcacgttccaaacacttcttatgtcatc
ccagcaggttatcacgttttggtttctccaggttacactcatttaagagacgaatacttc
cctaatgctcaccaattcaacattcaccgttggaacaaagattctgcctcctcttattcc
gtcggtgaagaagtcgattacggtttcggtgccatttctaagggtgtcagctctccatac
ttacctttcggtggtggtagacacagatgtatcggtgaacactttgcttactgtcagcta
ggtgttctaatgtccatttttatcagaacattaaaatggcattacccagagggtaagacc
gttccacctcctgactttacatctatggttactcttccaaccggtccagccaagatcatc
tgggaaaagagaaatccagaacaaaagatctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (3)   
   KEGG MODULE (3)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   NAGAHAMA-H (2)   
   NAGAHAMA-S (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (8)   
   PDB (8)   
Protein domain (1)   
   Pfam (1)   
All databases (58)   

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