KEGG   Saccharomyces cerevisiae (budding yeast): YML126C
Entry
YML126C           CDS       T00005                                 
Symbol
ERG13, HMGS
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase
  KO
K01641  hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00280  Valine, leucine and isoleucine degradation
sce00650  Butanoate metabolism
sce00900  Terpenoid backbone biosynthesis
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
Module
sce_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    YML126C (ERG13)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    YML126C (ERG13)
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    YML126C (ERG13)
Enzymes [BR:sce01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.10  hydroxymethylglutaryl-CoA synthase
     YML126C (ERG13)
SSDB
Motif
Pfam: HMG_CoA_synt_C HMG_CoA_synt_N
Other DBs
NCBI-GeneID: 854913
NCBI-ProteinID: NP_013580
SGD: S000004595
UniProt: P54839
Position
XIII:complement(19060..20535)
AA seq 491 aa
MKLSTKLCWCGIKGRLRPQKQQQLHNTNLQMTELKKQKTAEQKTRPQNVGIKGIQIYIPT
QCVNQSELEKFDGVSQGKYTIGLGQTNMSFVNDREDIYSMSLTVLSKLIKSYNIDTNKIG
RLEVGTETLIDKSKSVKSVLMQLFGENTDVEGIDTLNACYGGTNALFNSLNWIESNAWDG
RDAIVVCGDIAIYDKGAARPTGGAGTVAMWIGPDAPIVFDSVRASYMEHAYDFYKPDFTS
EYPYVDGHFSLTCYVKALDQVYKSYSKKAISKGLVSDPAGSDALNVLKYFDYNVFHVPTC
KLVTKSYGRLLYNDFRANPQLFPEVDAELATRDYDESLTDKNIEKTFVNVAKPFHKERVA
QSLIVPTNTGNMYTASVYAAFASLLNYVGSDDLQGKRVGLFSYGSGLAASLYSCKIVGDV
QHIIKELDITNKLAKRITETPKDYEAAIELRENAHLKKNFKPQGSIEHLQSGVYYLTNID
DKFRRSYDVKK
NT seq 1476 nt   +upstreamnt  +downstreamnt
atgaaactctcaactaaactttgttggtgtggtattaaaggaagacttaggccgcaaaag
caacaacaattacacaatacaaacttgcaaatgactgaactaaaaaaacaaaagaccgct
gaacaaaaaaccagacctcaaaatgtcggtattaaaggtatccaaatttacatcccaact
caatgtgtcaaccaatctgagctagagaaatttgatggcgtttctcaaggtaaatacaca
attggtctgggccaaaccaacatgtcttttgtcaatgacagagaagatatctactcgatg
tccctaactgttttgtctaagttgatcaagagttacaacatcgacaccaacaaaattggt
agattagaagtcggtactgaaactctgattgacaagtccaagtctgtcaagtctgtcttg
atgcaattgtttggtgaaaacactgacgtcgaaggtattgacacgcttaatgcctgttac
ggtggtaccaacgcgttgttcaactctttgaactggattgaatctaacgcatgggatggt
agagacgccattgtagtttgcggtgatattgccatctacgataagggtgccgcaagacca
accggtggtgccggtactgttgctatgtggatcggtcctgatgctccaattgtatttgac
tctgtaagagcttcttacatggaacacgcctacgatttttacaagccagatttcaccagc
gaatatccttacgtcgatggtcatttttcattaacttgttacgtcaaggctcttgatcaa
gtttacaagagttattccaagaaggctatttctaaagggttggttagcgatcccgctggt
tcggatgctttgaacgttttgaaatatttcgactacaacgttttccatgttccaacctgt
aaattggtcacaaaatcatacggtagattactatataacgatttcagagccaatcctcaa
ttgttcccagaagttgacgccgaattagctactcgcgattatgacgaatctttaaccgat
aagaacattgaaaaaacttttgttaatgttgctaagccattccacaaagagagagttgcc
caatctttgattgttccaacaaacacaggtaacatgtacaccgcatctgtttatgccgcc
tttgcatctctattaaactatgttggatctgacgacttacaaggcaagcgtgttggttta
ttttcttacggttccggtttagctgcatctctatattcttgcaaaattgttggtgacgtc
caacatattatcaaggaattagatattactaacaaattagccaagagaatcaccgaaact
ccaaaggattacgaagctgccatcgaattgagagaaaatgcccatttgaagaagaacttc
aaacctcaaggttccattgagcatttgcaaagtggtgtttactacttgaccaacatcgat
gacaaatttagaagatcttacgatgttaaaaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (5)   
   KEGG MODULE (3)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   NAGAHAMA-H (4)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (50)   

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