KEGG   Saccharomyces cerevisiae (budding yeast): YGL040C
Entry
YGL040C           CDS       T00005                                 
Symbol
HEM2, OLE4, SLU1
Name
(RefSeq) porphobilinogen synthase HEM2
  KO
K01698  porphobilinogen synthase [EC:4.2.1.24]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00860  Porphyrin metabolism
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
sce01240  Biosynthesis of cofactors
Module
sce_M00868  Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    YGL040C (HEM2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sce04147]
    YGL040C (HEM2)
Enzymes [BR:sce01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.24  porphobilinogen synthase
     YGL040C (HEM2)
Exosome [BR:sce04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   YGL040C (HEM2)
SSDB
Motif
Pfam: ALAD
Other DBs
NCBI-GeneID: 852842
NCBI-ProteinID: NP_011475
SGD: S000003008
UniProt: P05373
Structure
Position
VII:complement(419527..420555)
AA seq 342 aa
MHTAEFLETEPTEISSVLAGGYNHPLLRQWQSERQLTKNMLIFPLFISDNPDDFTEIDSL
PNINRIGVNRLKDYLKPLVAKGLRSVILFGVPLIPGTKDPVGTAADDPAGPVIQGIKFIR
EYFPELYIICDVCLCEYTSHGHCGVLYDDGTINRERSVSRLAAVAVNYAKAGAHCVAPSD
MIDGRIRDIKRGLINANLAHKTFVLSYAAKFSGNLYGPFRDAACSAPSNGDRKCYQLPPA
GRGLARRALERDMSEGADGIIVKPSTFYLDIMRDASEICKDLPICAYHVSGEYAMLHAAA
EKGVVDLKTIAFESHQGFLRAGARLIITYLAPEFLDWLDEEN
NT seq 1029 nt   +upstreamnt  +downstreamnt
atgcatacagctgaatttttggaaacagaaccaacagaaatctcatctgttctagcaggt
ggttataatcacccactgctgagacagtggcaaagtgagcgtcaactgactaagaacatg
ttgatttttccgctattcatctccgataatccagatgactttactgaaattgactctcta
cctaatatcaatagaatcggtgtaaataggctaaaagactacttaaagccattagtggcc
aagggtttgcgttctgtgatcttgtttggtgtgcctctcatccctggtaccaaggatcca
gtgggtacagcggctgacgatcctgcagggccagtcattcaaggtattaaattcattcgt
gagtatttccctgaactgtatattatttgcgatgtctgtctctgtgaatacacttctcat
ggccattgcggggttctatacgatgatggtactattaatagagaacgtagtgtctctaga
ttagcagctgtggcagttaactacgctaaagctggtgcgcactgtgtggctcccagtgat
atgatcgatggtaggatcagagatattaaacgaggcttaataaatgcaaacttggctcac
aagaccttcgtgttatcctatgcagctaagtttagcggtaatctatatgggccattccgt
gatgctgcttgttcagctccttcgaatggtgataggaaatgttaccaattacctcctgcc
ggtcgtggcctggcacgtagggcgttggaaagggatatgagtgaaggtgccgacggtatt
attgttaagccttccactttctacttagatataatgagggatgcaagtgaaatttgtaaa
gacttaccaatctgcgcatatcacgtgtcgggcgaatacgcaatgttacatgctgcagct
gaaaaaggtgttgttgatttgaagacaattgcctttgaatctcatcaaggtttcttgagg
gcgggtgccagattaatcatcacttatttggctcctgagttcctagactggttagatgaa
gaaaactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (4)   
   KEGG MODULE (4)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (12)   
   PDB (12)   
Protein domain (1)   
   Pfam (1)   
All databases (41)   

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