KEGG   Saccharomyces cerevisiae (budding yeast): YIL125W
Entry
YIL125W           CDS       T00005                                 
Symbol
KGD1, OGD1
Name
(RefSeq) alpha-ketoglutarate dehydrogenase KGD1
  KO
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce00020  Citrate cycle (TCA cycle)
sce00785  Lipoic acid metabolism
sce01100  Metabolic pathways
sce01110  Biosynthesis of secondary metabolites
sce01200  Carbon metabolism
sce01210  2-Oxocarboxylic acid metabolism
Module
sce_M00009  Citrate cycle (TCA cycle, Krebs cycle)
sce_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:sce00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    YIL125W (KGD1)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    YIL125W (KGD1)
Enzymes [BR:sce01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     YIL125W (KGD1)
SSDB
Motif
Pfam: E1_dh OxoGdeHyase_C Transket_pyr 2-oxogl_dehyd_N Cdh1_DBD_1
Other DBs
NCBI-GeneID: 854681
NCBI-ProteinID: NP_012141
SGD: S000001387
UniProt: P20967
Position
IX:122689..125733
AA seq 1014 aa
MLRFVSSQTCRYSSRGLLKTSLLKNASTVKIVGRGLATTGTDNFLSTSNATYIDEMYQAW
QKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSISNFPQGTEAAPLGTAMTGSVDENVS
IHLKVQLLCRAYQVRGHLKAHIDPLGISFGSNKNNPVPPELTLDYYGFSKHDLDKEINLG
PGILPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQY
TVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIV
LGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLGMNYQRPTTSGKYV
NLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALGVLLHGDAAFAGQGVVYETMG
FLTLPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEAVTF
IFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAKQKSVIDVYTEKLI
SEGTFSKKDIDEHKKWVWNLFEDAFEKAKDYVPSQREWLTAAWEGFKSPKELATEILPHE
PTNVPESTLKELGKVLSSWPEGFEVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLV
LDGQNVRVSGEDVERGTFSQRHAVLHDQQSEAIYTPLSTLNNEKADFTIANSSLSEYGVM
GFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQ
GPEHSSGRLERFLQLANEDPRYFPSEEKLQRQHQDCNFQVVYPTTPANLFHILRRQQHRQ
FRKPLALFFSKQLLRHPLARSSLSEFTEGGFQWIIEDIEHGKSIGTKEETKRLVLLSGQV
YTALHKRRESLGDKTTAFLKIEQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAY
TEPRLHTTLKETDKYKDFKVRYCGRNPSGAVAAGSKSLHLAEEDAFLKDVFQQS
NT seq 3045 nt   +upstreamnt  +downstreamnt
atgctaaggttcgtgtcttcgcaaacctgccggtatagttcaagaggactattaaaaaca
tctttacttaaaaatgcatctactgtcaaaattgtcggaagagggttagccaccactggt
acagataattttctatcgacatcaaatgccacctatatcgatgaaatgtaccaagcttgg
caaaaagacccatcttcagtccatgtttcatgggacgcatatttcaagaatatgtctaac
ccaaagattccagctacaaaggcttttcaggctcctcccagtatcagtaactttccccag
ggtaccgaagcagctcccttagggaccgcaatgactggttcagtagatgagaacgtctcc
attcatctaaaagtgcaattgctatgtagagcttaccaagttagaggtcatttaaaagcc
catatagatcctttagggatctcatttggtagtaataaaaataaccctgttcctccggaa
ttgactctagactactacggctttagcaaacacgatcttgataaagaaatcaacctagga
cctggtatcctgccaaggtttgcaagggacgggaaatctaaaatgtctctgaaagagatt
gtggatcatctagaaaagttatattgttcctcttatggggtacaatacacacatattcca
tctaagcaaaagtgtgattggttaagagagagaattgagattcctgaaccttaccaatat
acagtggaccaaaagagacaaatcttagatagattaacatgggccacttcttttgagtca
ttcttatctacaaaatttccaaatgataagaggttcggtttagaaggtttggaaagtgtt
gttccaggtattaaaactttggttgatcgttctgttgaattgggtgtagaagatattgtt
ttgggtatggctcaccgtggtagattgaacgttttatccaatgtggtccgtaaaccaaat
gaatctattttttctgaatttaagggttcgagcgctcgcgatgatattgaaggatcgggt
gatgtcaagtaccatttgggtatgaactaccaaagaccaactacgtctggtaagtacgtc
aatttatcgctggtggcaaatccttctcatttagaatcccaagatccagttgttcttggt
agaactagagctttattgcatgccaagaacgatttgaaggaaaaaacaaaggccttaggt
gtgttattacatggtgatgctgcttttgctgggcagggtgttgtttatgaaaccatgggt
ttcttgaccctaccagaatactctactggtggtactattcatgttattacaaacaaccag
atcggattcactacggatccaagatttgcaaggtccacaccatatccttccgatttggct
aaggccattgatgccccaattttccatgttaacgctaatgacgtggaagctgtgaccttt
attttcaatttagccgcagaatggagacataagttccacacagatgccataattgatgtc
gttggttggagaaaacatggacataatgaaaccgatcagccatcgtttactcaaccatta
atgtacaaaaaaattgcaaaacaaaaatctgtcattgacgtctatacggaaaaattgata
agtgaaggcacattttctaaaaaagatattgatgagcacaagaaatgggtatggaactta
tttgaagatgctttcgaaaaggcaaaggattacgtcccatctcaaagagaatggttaact
gctgcctgggaaggattcaaatccccaaaggaattggccactgagatattaccacatgaa
ccaactaatgttccagagagtactttgaaagaactaggtaaggtactctcttcgtggcca
gaaggttttgaagtgcacaaaaatctaaagagaattttgaaaaatagaggaaaatctatt
gagacaggtgaaggcatcgattgggccaccggtgaagcattagcgttcggtacattggtt
ttggatggtcagaacgttagggtttccggtgaagatgtagaaagaggtacattttctcaa
cgtcatgcagtcttgcatgaccaacaatctgaagccatttacacaccgctaagcactctg
aataatgaaaaggcagacttcaccattgcaaattcctcgttatctgagtacggtgtaatg
ggtttcgaatatggttattcgctaacctccccagattatctagtcatgtgggaggctcaa
ttcggtgactttgcaaatacagcacaggttattattgaccaatttattgccggtggtgaa
caaaaatggaagcaacgctctggtttagttttgtctttaccccatggttatgatggccag
gggccagaacattcgtctggtagattggaaagattcttgcaactagccaatgaagaccca
agatatttcccatctgaagaaaagctacagagacaacatcaggattgtaatttccaggtt
gtttatccaactacgcctgctaatttattccacattctaaggagacagcaacatcgtcaa
ttccgtaaaccattggcgttattcttttctaaacagctgctgcgtcacccattggccaga
tcatctctttccgaattcactgaaggcggattccaatggattatcgaagatattgaacat
ggaaaaagtattggtacgaaagaggaaaccaagagattagttttgctgagtggccaagtg
tacactgccctacataaaagacgtgaaagtttgggtgataagaccactgctttcttaaag
attgaacagctgcacccattcccatttgctcagctacgtgattcattaaattcttatcca
aacttggaagaaattgtttggtgccaggaagagccattgaacatgggttcgtgggcatac
acagaaccacgcttacacacaacattaaaagaaacggataaatataaggatttcaaggtc
agatactgtggtagaaacccaagtggtgctgttgctgccggtagcaaatcactacatttg
gccgaagaagatgcctttttgaaagatgttttccaacaatcctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (53)   

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